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Astros vs Rangers Prediction, Pick, MLB Odds for Wednesday, May 27

Astros vs Rangers Prediction, Pick, MLB Odds for Wednesday, May 27 article feature image
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The Texas Rangers host the Houston Astros on May 27, 2026. First pitch from Globe Life Field is scheduled for 8:05 p.m. EDT. The game will be broadcast on SCHN.

The Rangers are favored by -156 on the moneyline and by -1.5 on the run line. The Astros are +130 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.

Find my MLB picks and Astros vs Rangers prediction below, as well as probable pitchers, weather report, and more.


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Astros vs Rangers Prediction

  • Astros vs Rangers Pick: Under 7.5 Total Runs -110 (FanDuel, Play to -115)

My Astros vs Rangers best bet is Under 7.5 Runs. Make sure to find the best odds by checking our live MLB odds page.


Astros vs Rangers Odds

Astros Logo
May 27, 2026
8:05 p.m. EDT
SCHN
Rangers Logo
Astros Odds
SpreadTotalMoneyline
+1.5
+130
7.5
-125o / -105u
+130
Rangers Odds
SpreadTotalMoneyline
-1.5
-156
7.5
-125o / -105u
-156
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Astros vs Rangers moneyline: Astros +130, Rangers -156
  • Astros vs Rangers over/under: 7.5 (-125o / -105u)
  • Astros vs Rangers spread: Rangers -1.5 (+130 ), Astros +1.5 (-156)

Astros vs Rangers Probable Pitchers

RHP Mike Burrows (HOU)StatRHP Jacob deGrom (TEX)
2-6W-L24-29
-0.1fWAR (FanGraphs)0.7
5.75/4.12ERA / xERA3.86/3.86
5.37/4.47FIP / xFIP4.21/3.24
11.3%K-BB%24.7%
38.1%GB%26.6%
.327BABIP.250
93Stuff+110
97Location+113

Astros vs Rangers MLB Betting Preview

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Houston Astros Betting Preview: Burrows Struggling to Settle

After pitching to an ERA of 3.94 with a 3.86 across 96 innings last season, Burrows has struggled to settle into form in his first campaign with the Astros. He holds relatively average underlying results with a 4.12 xERA and 4.47 xFIP, but has suffered from a career-high BABIP and a career-low strand rate.

The Astros' depleted lineup has continued to struggle over the last month, as they have hit to a wRC+ of 92 and hold the third-lowest BB/K ratio in MLB. Yordan Alvarez has been exceptional with a 1.045 OPS, but is being asked to compensate for some significant holes further down the lineup.

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Texas Rangers Betting Preview: DeGrom the Key for Rangers

Jacob DeGrom will look to continue his dominance at Globe Life Field on Wednesday, where he has pitched to an ERA of 1.14 and a WHIP of 0.59 across 23 and 2/3 innings this season. DeGrom also pitched to an ERA of 2.35 across 88 innings at home last season.

Globe Life has been the most pitcher-friendly ballpark in MLB by a wide margin this season, with a Park Factor rating of 86. The under holds a 16-6-1 record at Globe Life this season and has yielded a +37.2% ROI.

While the Astros' injury concerns have been widely covered, the Rangers are currently without some key pieces, including Corey Seager, Wyatt Langford, and Josh Smith, though collectively, the three have posted disappointing results at the plate this season.

Texas holds a wRC+ of 79 at home this season and has slugged just .328 playing in a park that seems to contain the majority of well-hit balls.


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Astros vs Rangers Pick, Betting Analysis

While Tuesday's matchup was a shootout, it was by a wide margin the season's highest-scoring matchup at Globe Life, and it seems logical to expect things to return to normal on Wednesday.

Both depleted offenses have been in relatively poor form of late, and the Rangers' distinct lack of power at home should help Burrows settle into this matchup.

DeGrom has been nearly untouchable at home, where he clearly feels quite comfortable leaning into an aggressive approach in a ballpark that does not yield many long balls.

At -110, there appears to be value in betting the under on Wednesday, targeting a trend that has yielded a 37% ROI this season.

Pick: Under 7.5 Runs -110 (FanDuel, Play to -115)


Astros vs Rangers Weather


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