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Dodgers vs Twins Prediction, Pick, MLB Odds for Monday, June 22

Dodgers vs Twins Prediction, Pick, MLB Odds for Monday, June 22 article feature image
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Photo Credit: Rick Scuteri-Imagn Images
Pictured: Byron Buxton reacts after hitting a grand slam

The Minnesota Twins host the Los Angeles Dodgers on June 22, 2026. First pitch from Target Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on SportsNet LA.

The Dodgers are favored by -154 on the moneyline and by -1.5 on the run line. The Twins are +129 on the moneyline and +1.5 on the run line. The total is set at 9.5 runs.

Find my MLB picks and Dodgers vs Twins prediction below, as well as probable pitchers, weather report, and more.


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Dodgers vs Twins Prediction

  • Dodgers vs Twins Pick: Over 9.5 (-100, FanDuel)

My Dodgers vs Twins best bet is 10+ total runs. Make sure to find the best odds by checking our live MLB odds page.


Dodgers vs Twins Odds

Dodgers Logo
June 22, 2026
7:40 p.m. EDT
SportsNet LA
Twins Logo
Dodgers Odds
SpreadTotalMoneyline
-1.5
-125
9.5
-105o / -115u
-154
Twins Odds
SpreadTotalMoneyline
+1.5
+105
9.5
-105o / -115u
+129
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Dodgers vs Twins moneyline: Dodgers -154, Twins +129
  • Dodgers vs Twins over/under: 9.5 (-105o / -115u)
  • Dodgers vs Twins spread: Dodgers -1.5 (+105), Twins +1.5 (-125)

Dodgers vs Twins Probable Pitchers

Eric LauerStatZebby Matthews
2-5W-L3-4
-0.6fWAR (FanGraphs)0.3
5.37 / 5.36ERA / xERA4.78 / 3.81
6.41 / 5.27FIP / xFIP4.70 / 4.30
7.6K-BB%14
29.5GB%37.9
.233BABIP.272
88Stuff+95
102Location+100

Dodgers vs Twins MLB Betting Preview

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Dodgers vs Twins Pick, Betting Analysis

This is Eric Lauer vs. Zebby Matthews. And this game is the highest-scoring affair in the sim model. The sims have the Dodgers winning 6.3 to 5.4, for a total of nearly 12 runs.

And I think that's because both offenses match up very well with the pitching they're facing tonight.

Zebby is a bad righty taking on the Dodgers. That almost never goes well. He's also a fly-ball pitcher, which is even more terrifying given the HR/FB trend we've identified.

Lauer has really rough splits this year. He's struck out just 14.7% of righties while allowing a .353 xwOBA and carrying a tiny 29% ground-ball rate. He gets hit in the air so, so much against righties. And the Twins project to have nine righties in the lineup. That's the entire lineup, you guys.

The top two projected hitters in the sims are Shohei Ohtani and Byron Buxton. Only those two and Jackson Chourio project for more than 12 DraftKings points tonight. So the leadoff men are likely to feast, and there are plenty of other threats in these lineups given the matchups.

So first of all:

Pick: Over 9.5 (-100, FanDuel)

But if you want to go for the high-upside home run parlay, which I know a lot of you do, I like Buxton + Ohtani, even though they are both ridiculously priced at +201. If that duo hits, you're at just +750 together. But they're the top two projected home run hitters today by a good margin.


Dodgers vs Twins Weather


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About the Author
Jon AndersonVerified Action Expert

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