Marlins vs Padres Prediction, Pick, Odds for Wednesday, May 28

Marlins vs Padres Prediction, Pick, Odds for Wednesday, May 28 article feature image
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Credit: Imagn Images. Pictured: Miami Marlins SP Sandy Alcantara.

The San Diego Padres host the Miami Marlins on May 28, 2025. First pitch from PETCO Park is scheduled for 4:10 p.m. EDT; the game will be broadcast on SDPA.

Read our Marlins vs Padres prediction and 2025 MLB pick below.

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My Marlins vs Padres Prediction

  • Marlins vs Padres Picks: Padres F5 TT o2.5 (+105, DraftKings)

My Marlins vs Padres best bet is on San Diego's first-half team total. Make sure to find the best odds by checking our live MLB odds page.


Marlins vs Padres Odds

Marlins Logo
May 28, 2025
4:10 p.m. EDT
SDPA
Padres Logo
Marlins Odds
SpreadTotalMoneyline
+1.5
+125
8.5
-105o / -115u
+140
Padres Odds
SpreadTotalMoneyline
-1.5
-155
8.5
-105o / -115u
-166
Odds via DraftKings. Get up-to-the-minute MLB odds here.
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Brit Devine’s Marlins vs Padres Preview

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San Diego Padres Team Total Prop

Here are Marlins starting pitcher Sandy Alcantara’s earned run counts over the past eight starts: 5, 4, 4, 5, 7, 3, 6, 4.

He’s allowed at least four earned runs in seven of his eight starts, and he allowed three earned in the other start.

The books rarely bless us with a number like this one, and it’s a number I have to hammer.

Alcantara’s return from Tommy John surgery hasn’t been smooth, but the Fish are forced to keep rolling him out there, hoping he can turn it around so they can deal him for value at the deadline.

San Diego’s lineup has cooled off recently, but the Padres are poised for a breakout performance against a broken pitcher.

I’m placing three units on this play — it’s one of the strongest plays I have seen all season.

Pick: Padres F5 TT o2.5 (+105, DraftKings)

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