Brewers vs Pirates Predictions, Parlay, Picks, Odds for Thursday, May 22

Brewers vs Pirates Predictions, Parlay, Picks, Odds for Thursday, May 22 article feature image
Credit:

Photo by Mark Hoffman/Milwaukee Journal Sentinel / USA TODAY NETWORK via Imagn Images. Pictured: Rhys Hoskins

The Pittsburgh Pirates host the Milwaukee Brewers on May 22, 2025. First pitch from PNC Park is scheduled for 6:40 p.m. ET; the game will be broadcast on SportsNet PT.

Find my MLB betting preview and Brewers vs Pirates prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Brewers vs Pirates Predictions, Parlay

  • Pirates ML
  • Rhys Hoskins 1+ Hit

Parlay Odds: +250 (BetMGM)


Brewers vs Pirates Odds

Brewers Logo
Thursday, May 22
6:40 p.m. ET
SportsNet PT
Pirates Logo
Brewers Odds
SpreadTotalMoneyline
-1.5
+135
9
-110o / -110u
-125
Pirates Odds
SpreadTotalMoneyline
+1.5
-160
9
-110o / -110u
+105
Odds via BetMGM. Get up-to-the-minute MLB odds here.
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Brewers vs Pirates Preview, Parlay Picks

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Pirates ML

This is the first of a four-game series between Pittsburgh and Milwaukee.

The Pirates are 17-33 this year but 11-14 at PNC Park, while the Brewers are 24-26 this year but just 9-16 on the road.

Mike Burrows takes the mound for the Pirates on Thursday in his first career start.

The Pirates have won two straight and their bats will lead Burrows to victory in this one. Take the Pirates moneyline.


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Rhys Hoskins 1+ Hit

Rhys Hoskins has been raking off right-handed pitchers this year, with a .311 average and .915 OPS.

Hoskins has been on fire in the past week, hitting .350, which is well above his standard.

The Brewers' first baseman will have a big game versus Burrows in his first career start.


Brewers vs Pirates Parlay

  • Pirates ML
  • Rhys Hoskins 1+ Hit

Parlay Odds: +250 (BetMGM)


Brewers vs Pirates Betting Trends


Brewers vs Pirates Weather


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