The Chicago White Sox host the Minnesota Twins on May 25, 2026. First pitch from Rate Field is scheduled for 2:10 p.m. EDT. The game will be broadcast on CHSN.
The Twins are favored by -110 on the moneyline and by -1.5 on the run line. The White Sox are -106 on the moneyline and +1.5 on the run line. The total is set at 8 runs.
Find my MLB picks and Twins vs White Sox prediction below, as well as probable pitchers, weather report, and more.
Twins vs White Sox Prediction
- Twins vs White Sox Pick: Under 8 (-106 or Better)
My Twins vs White Sox best bet is on the Under. Make sure to find the best odds by checking our live MLB odds page.
Twins vs White Sox Odds
| Twins Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +150 | 8 -120o / -102u | -110 |
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -182 | 8 -120o / -102u | -106 |
- Twins vs White Sox moneyline: Twins -110, White Sox -106
- Twins vs White Sox over/under: 8 (-120 / -102)
- Twins vs White Sox spread: Twins -1.5 (+150), White Sox +1.5 (-182)
Twins vs White Sox Probable Pitchers
| Zebby Matthews (RHP, MIN) | Stat | Anthony Kay (LHP, CWS) |
|---|---|---|
| 1-1 | W-L | 3-1 |
| 0.4 | fWAR (FanGraphs) | 0.1 |
| 1.38 / 2.31 | ERA / xERA | 4.27 / 5.91 |
| 2.62 / 3.22 | FIP / xFIP | 5.30 / 5.18 |
| 20.8% | K-BB% | 5.7% |
| 38.9% | GB% | 42.1% |
| .229 | BABIP | .277 |
| 97 | Stuff+ | 105 |
| 104 | Location+ | 100 |
Twins vs White Sox MLB Betting Preview
Our own Sean Zerillo projects some value on the Under in this Memorial Day matchup.
While the consensus line sits around 8, Zerillo projects this total around 7.6, providing around a 2% edge against the market.
As a reminder, you can get all of Zerillo's PRO lines on the MLB projections tab.
Twins vs White Sox Pick, Betting Analysis
This wager is partially based on the wind, which is blowing directly in from center field toward home plate.
The wind hopefully knocks down plenty of fly balls because the White Sox have been hammering homers all season — they rank third among MLB lineups in home runs (70).
Meanwhile, the Twins lineup has fallen off a cliff in May (.301 xwOBA, -.036 xwOBA over Expectation), after a red-hot April (.323 xwOBA, -.016 xwOBA over Expectation).
Zerillo says we should bet the Under 8 at -106 or better.
Pick: Under 8 (-106 or Better)
