The Chicago White Sox host the Minnesota Twins on May 26, 2026. First pitch from Rate Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on MNNT.
The Twins are favored by -115 on the moneyline and by -1.5 on the run line. The White Sox are -104 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.
Find my MLB picks and Twins vs White Sox prediction below, as well as probable pitchers, weather report, and more.
Twins vs White Sox Prediction
- Twins vs White Sox Pick: Colson Montgomery Over 0.5 Home Runs
My Twins vs White Sox best bet is HR Prop on Chicago's shortstop. Make sure to find the best odds by checking our live MLB odds page.
Twins vs White Sox Odds
| Twins Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -176 | 7.5 -117o / -102u | -115 |
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +145 | 7.5 -117o / -102u | -104 |
- Twins vs White Sox moneyline: Twins -115, White Sox -104
- Twins vs White Sox over/under: 7.5 (-117o / -102u)
- Twins vs White Sox spread: Twins -1.5 (+145), White Sox +1.5 (-176)
Twins vs White Sox Probable Pitchers
| RHP Joe Ryan (MIN) | Stat | RHP Sean Burke (CWS) |
|---|---|---|
| 3-3 | W-L | 2-3 |
| 1.8 | fWAR (FanGraphs) | 1.1 |
| 3.02 / 2.87 | ERA / xERA | 4.08 / 4.08 |
| 2.51 / 3.49 | FIP / xFIP | 3.64 / 4.19 |
| 20.9% | K-BB% | 14.3% |
| 38.4% | GB% | 35.3% |
| .264 | BABIP | .292 |
| 108 | Stuff+ | 97 |
| 106 | Location+ | 105 |
Twins vs White Sox MLB Betting Preview, Analysis
Montgomery has been one of the best HR hitters in the league since getting called up, and these odds are far too high.
The weather should be slightly below average for hitting, but the matchup vs. Joe Ryan is a plus for lefty power. Ryan is an extreme fly-ball pitcher with above-average splits.
He grades out as a matchup that is well above average for lefties, and I have the true odds here around +300, making this a great bet.
Pick: Colson Montgomery Over 0.5 Home Runs
