MLB Picks & Predictions: Blue Jays vs. Royals & Mariners vs. Astros Top Smartest Wednesday Bets

MLB Picks & Predictions: Blue Jays vs. Royals & Mariners vs. Astros Top Smartest Wednesday Bets article feature image
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Steph Chambers/Getty Images. Pictured: Julio Rodriguez

Wednesday's MLB slate offers two afternoon matchups before the meat of the schedule gets underway tonight.

Interestingly, when it comes to the smartest Wednesday MLB bets, one — Blue Jays vs. Royals — comes from an afternoon game, while the second — Mariners vs. Astros — gets underway early tonight.

Using our MLB PRO betting tools, let's examine these games in more detail, including why they're among Wednesday's smartest baseball bets.

MLB Picks & Predictions for Wednesday

*Odds and betting data as of Wednesday morning

Blue Jays vs. Royals MLB Pick

2:10 p.m. ET | YouTube

Wednesday's Blue Jays vs. Royals betting model edge is not only big, it could end up as the biggest of today's entire MLB slate.