Pirates vs Diamondbacks Prediction, Odds, Picks, MLB Betting Preview

Pirates vs Diamondbacks Prediction, Odds, Picks, MLB Betting Preview article feature image
Credit:

Kyle Ross-Imagn Images. Pictured: Pittsburgh’s Oneil Cruz.

The Arizona Diamondbacks host the Pittsburgh Pirates on May 28, 2025. First pitch from Chase Field is scheduled for 3:40 p.m. ET; the game will be broadcast on SportsNet PT and MLB.TV.

The Diamondbacks enter as -135 favorites on the moneyline with the over/under sitting at 7.5.

Find my Pirates vs Diamondbacks prediction and MLB betting preview below, as well as probable pitchers, betting trends, injury reports and more.


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Pittsburgh Pirates vs Arizona Diamondbacks Prediction, Picks

  • Pirates vs Diamondbacks Pick: Oneil Cruz Over 0.5 Doubles (+480)

My Pirates vs Diamondbacks best bet is on Pittsburgh shortstop Oneil Cruz to hit at least one double in this game. Make sure to find the best odds by checking our live MLB odds page.


Pirates vs Diamondbacks Odds, Spread, Lines

Pirates Logo
Wednesday, May 28
3:40 p.m. ET
MLB.TV
Diamondbacks Logo
Pirates Odds
Run LineTotalMoneyline
+1.5
-220
7.5
-107o / -113u
+110
Diamondbacks Odds
Run LineTotalMoneyline
-1.5
+170
7.5
-107o / -113u
-129
Odds via BetRivers. Get up-to-the-minute MLB odds here.
BetRivers Logo

Pirates vs Diamondbacks Projected Pitchers

Pirates vs Diamondbacks Preview for Wednesday, May 28

I cashed a 412-1 parlay a few days ago using PRO Projections. The final leg was Action PRO’s top recommendation to hit a double: Pirates star Oneil Cruz. 

For Wednesday’s Pirates vs. Diamondbacks matchup, perhaps the best bet is again on Cruz hitting a double, available at +480 odds on FanDuel.

According to PRO Projections — our proprietary betting model that leverages expert MLB insights and market comparisons —Cruz’s expected probability to record a double stands at 0.28, or 28%.

This suggests a significant value opportunity given the current market price.

Cruz is widely recognized for his power-hitting ability. Recently, he launched the hardest-hit home run of the StatCast era at roughly 122 mph, underscoring his raw power.

However, rather than betting on a homer, the best value play today is his potential to hit a double. Chase Field is an ideal environment for doubles — it’s the top park in MLB for doubles this year and ranks third over the last three seasons.


Pirates vs Diamondbacks Best Bets, Pick

Batting primarily as the lead-off hitter, Cruz benefits from roughly five plate appearances per game, increasing his opportunities to get on base with extra-base hits.

When comparing our projections for extra-base hits today, Cruz’s double stands out as the top bet, boasting a 7.2% edge between our calculated fair odds (+257) and the market price (+480).

Pick: Oneil Cruz Over 0.5 Doubles (+480)


Pirates vs Diamondbacks Betting Trends to Know



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About the Author
Alex began his career as a freelancer before becoming a columnist, reporter, and breaking news writer for FanRag Sports, and later the leading gambling writer at theScore. He joined the Action Network as a senior news editor, handling breaking news and the sports betting market's reactions. Alex also works on Action Network’s PRO projections, transforming subscription-based models into user-friendly content.

Follow Alex Kolodziej @KolodziejAlex on Twitter/X.

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