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Padres vs Phillies Prediction, Pick, MLB Odds for Thursday, June 4

Padres vs Phillies Prediction, Pick, MLB Odds for Thursday, June 4 article feature image
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The Philadelphia Phillies host the San Diego Padres on June 4, 2026. First pitch from Citizens Bank Park is scheduled for 1:05 p.m. EDT. The game will be broadcast on NBC 10.

The Phillies are favored by -200 on the moneyline and by -1.5 on the run line. The Padres are +168 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and Padres vs Phillies prediction below, as well as probable pitchers, weather report, and more.


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Padres vs Phillies Prediction

  • Padres vs Phillies Pick: Under 8.5

My Padres vs Phillies best bet is on the Under. Make sure to find the best odds by checking our live MLB odds page.


Padres vs Phillies Odds

Padres Logo
Thursday, Jun 4
1:05 p.m. ET
NBC 10
Phillies Logo
Padres Odds
SpreadTotalMoneyline
+1.5
-122
8.5
102o / -124u
+168
Phillies Odds
SpreadTotalMoneyline
-1.5
+102
8.5
102o / -124u
-200
Odds via FanDuel. Get up-to-the-minute MLB odds here.
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  • Padres vs Phillies moneyline: Padres +168, Phillies -200
  • Padres vs Phillies over/under: 8.5 (+102 / -124)
  • Padres vs Phillies spread: Padres +1.5 (-122), Phillies -1.5 (+102)

Padres vs Phillies Probable Pitchers

Lucas Giolito (RHP, SDP)StatZack Wheeler (RHP, PHI)
2-0W-L4-1
-0.2fWAR (FanGraphs)0.9
4.97 / 5.04ERA / xERA2.27 / 3.18
7.28 / 7.25FIP / xFIP3.43 / 3.28
-10.5%K-BB%18.9%
26.3%GB%44.7%
.222BABIP.211
87Stuff+104
97Location+109

Padres vs Phillies MLB Betting Preview

This game triggered one of our Action PRO betting systems, powered by Evan Abrams:

In matchups between winning teams, sportsbooks often inflate totals due to perceived offensive capability, yet these teams also tend to have stronger pitching and tighter late-game execution — leading to a profitable edge on the Under.


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Padres vs Phillies Pick, Betting Analysis

Zack Wheeler is still pitching like one of the league’s best. Sure, his last start against the Dodgers looks iffy on the surface (four earned over six frames), but he actually posted his highest single-game Pitching+ mark of any start this season (127).

This is a great bounce-back spot for Wheeler against a Padres offense that has been in a slump for the better part of a month — the lineup has posted a league-low 76 wRC+ over the past month.

I’m no believer in Lucas Giolito, but the Padres have a great defense and an elite bullpen behind him. Plus, the Phillies haven’t been world-beaters in the batter’s box (88 wRC+ over the past 30 days).

Pick: Under 8.5


Padres vs Phillies Weather


Get the latest coverage on MLB Weather.
Author Profile
About the Author

Tanner McGrath covers college basketball, college football and Major League Baseball at Action Network. He is a contributor to Payoff Pitch, Action Network’s Major League Baseball betting podcast. He's been working in the space for more than five years with past journalism experience in Canadian collegiate sports, finance and economics. He has an obsession with America East basketball, betting the Miami Marlins and sweating out home underdogs.

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