The Baltimore Orioles host the St. Louis Cardinals on May 27, 2025. First pitch from Oriole Park at Camden Yards is scheduled for 6:35 p.m. EDT; the game will be broadcast on FDSMW.
Read our Cardinals vs Orioles prediction and MLB player prop home run pick below.
My Cardinals vs Orioles Prediction
- Cardinals vs Orioles Picks: Lars Nootbaar Home Run (+550, BetMGM)
My Cardinals vs Orioles best bet is on Lars Nootbaar to hit a home run. Make sure to find the best odds by checking our live MLB odds page.
Cardinals vs Orioles Odds, Spread
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +145 | 9 -110o / -110u | -118 |
| Orioles Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -175 | 9 -110o / -110u | -102 |
My Cardinals vs Orioles Betting Preview
St. Louis Cardinals Player Prop: Nootbaar Homer
Lars Nootbaar has been hitting well this season, and he’s in a good spot on Tuesday to go yard.
The ballpark is an upgrade for left-handed power hitters, and the weather shouldn’t be bad for hitting.
Orioles starting pitcher Tomoyuki Sugano has been crushed by lefties in his career, allowing a whopping 1.71 home runs per nine innings pitched to the side.
I make the fair odds on this home run prop under +500, making this a great bet.
Pick: Lars Nootbaar Home Run (+550, BetMGM)
