The Baltimore Orioles host the St. Louis Cardinals on May 28, 2025. First pitch from Oriole Park at Camden Yards is scheduled for 6:35 p.m. EDT; the game will be broadcast on MASN.
The Orioles enter as -112 favorites on the moneyline with the over/under sitting at 7.5.
Find my Cardinals vs Orioles prediction and MLB betting preview below, as well as probable pitchers, betting trends, injury reports and more.
St. Louis Cardinals vs Baltimore Orioles Prediction, Picks
- Cardinals vs Orioles Pick: Under 8
My Orioles vs. Cardinals best bet is for both teams to go under the total. Make sure to find the best odds by checking our live MLB odds page.
Cardinals vs Orioles Odds, Spread, Line
| Cardinals Odds | ||
|---|---|---|
| Run Line | Total | Moneyline |
-1.5 +160 | 7.5 -124o / +102o | -104 |
| Orioles Odds | ||
|---|---|---|
| Run Line | Total | Moneyline |
+1.5 -194 | 7.5 -124o / +102u | -112 |
Cardinals vs Orioles MLB Preview
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Cardinals vs Orioles Pick, Best Bets
Pick: Under 8
Cardinals vs Orioles Betting Trends to Watch
