The Los Angeles Angels host the St. Louis Cardinals on July 22, 2026. First pitch from Angel Stadium is scheduled for 4:07 p.m. EDT. The game will be broadcast on CARD.
The Cardinals are favored by -120 on the moneyline and by -1.5 on the run line. The Cardinals are -100 on the moneyline and -1.5 on the run line. The total is set at 9 runs.
Find my MLB picks and Cardinals vs Angels prediction below, as well as probable pitchers, weather report, and more.
Cardinals vs Angels Prediction
- Cardinals vs Angels Pick: Jordan Walker Over 1.5 Total Bases
My Cardinals vs Angels best bet is on St. Louis to win the first five innings and Walker to record 2+ total bases. Make sure to find the best odds by checking our live MLB odds page.
Cardinals vs Angels Odds
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +162 | 9 -115o / -105u | -100 |
| Angels Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +155 | 9 -115o / -105u | -120 |
- Cardinals vs Angels moneyline: Cardinals -100, Angels -120
- Cardinals vs Angels over/under: 9 (-115o / -105u)
- Cardinals vs Angels spread: Cardinals -1.5 (+155), Angels -1.5 (+155)
Cardinals vs Angels Probable Pitchers
| Hunter Dobbins | Stat | Reid Detmers |
|---|---|---|
| 1-1 | W-L | 3-6 |
| 0.2 | fWAR (FanGraphs) | 3 |
| 4.03 / 5.14 | ERA / xERA | 4.16 / 3.27 |
| 4.13 / 3.77 | FIP / xFIP | 3.22 / 3.71 |
| 13.7 | K-BB% | 20 |
| 43.5 | GB% | 34.8 |
| .305 | BABIP | .276 |
| 99 | Stuff+ | 105 |
| 101 | Location+ | 109 |
Cardinals vs Angels MLB Betting Preview
Cardinals vs Angels Pick, Betting Analysis
Angels’ left-hander Reid Detmers will take the mound, while the Cardinals will start righty Hunter Dobbins.
Detmers has struggled, currently running an underwhelming 4.16 ERA.
So, I'm willing to take a shot on Cards’ slugger Jordan Walker to find success at the plate.
Detmers’ arsenal features a slider-heavy, four-seam fastball mix that is often ineffective against right-handed hitters, particularly those who hit for power like Walker.
The reigning Home Run Derby Champ has a powerful right-handed bat with an overall hitting profile that is built for driving four-seamers and hanging sliders – two of Detmers’ favorite pitches.
Walker has been a force against left-handed pitching, using his length in the box to cover the outer half of the plate and pull high fastballs.
Though Detmers relies on his strikeout prowess and his ability to generate soft contact, Walker’s massive 6-foot-6 frame has allowed him to drive the ball deep versus southpaws.
Picks: Jordan Walker Over 1.5 Total bases (+120)
