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Blue Jays vs Nationals Prediction, Pick, MLB Odds for Wednesday, July 29

Blue Jays vs Nationals Prediction, Pick, MLB Odds for Wednesday, July 29 article feature image
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David Frerker-Imagn Images

Pictured: Vladimir Guerrero Jr.

The Washington Nationals host the Toronto Blue Jays on July 29, 2026. First pitch from Nationals Park is scheduled for 1:05 p.m. EDT. The game will be broadcast on NATS.

The Blue Jays are favored by -120 on the moneyline and by -1.5 on the run line. The Nationals are -100 on the moneyline and +1.5 on the run line. The total is set at 9.5 runs.

Find my MLB picks and Blue Jays vs Nationals prediction below, as well as probable pitchers, weather report, and more.


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Blue Jays vs Nationals Prediction

  • Blue Jays vs Nationals Pick: Vladimir Guerrero Jr. Over 1.5 Hits +Runs+RBI | Vladimir Guerrero Jr. Over 1.5 Total Bases | C.J. Abrams Over 1.5 Total Bases

My Blue Jays vs Nationals best bets are a trio of hitter props, including Vladimir Guerrero Jr. and C.J. Abrams. Make sure to find the best odds by checking our live MLB odds page.


Blue Jays vs Nationals Odds

Blue Jays Logo
July 29, 2026
1:05 p.m. EDT
NATS
Nationals Logo
Blue Jays Odds
SpreadTotalMoneyline
-1.5
-160
9.5
-102o / -118u
-120
Nationals Odds
SpreadTotalMoneyline
+1.5
+135
9.5
-102o / -118u
-100
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Blue Jays vs Nationals moneyline: Blue Jays -120, Nationals -100
  • Blue Jays vs Nationals over/under: 9.5 (-102o / -118u)
  • Blue Jays vs Nationals spread: Blue Jays -1.5 (+135), Nationals +1.5 (-160)

Blue Jays vs Nationals Probable Pitchers

Trey Yesavage (RHP)StatZack Littell (RHP)
4-5W-L7-8
1.2fWAR (FanGraphs)-0.8
3.92/3.31ERA / xERA5.17/6.27
4.15/4.57FIP / xFIP6.03/5.17
12.7K-BB%8.1
33.5GB%34.2
.226BABIP.256
108Stuff+83
90Location+101

Blue Jays vs Nationals MLB Betting Preview

The Nationals and Blue Jays will duke it out on Wednesday afternoon in the last of a three-game set at Nationals Park in Washington, D.C.

Nationals’ 30-year-old right-hander Zack Littell will take the mound, while the Jays plan to trot out young righty Trey Yesavage in a matchup I heavily favor targeting player prop markets as opposed to sides as my primary betting angles.

In 101 frames of work on the bump in 2026, Littell has been atrocious in his first season with the team.

Across his 21 outings this season, he has recorded a concerning 5.17 ERA mark to go along with a 1.34 WHIP.

My preferred handicapping approach for Wednesday’s interleague clash will be to target Jays’ superstar Vladimir Guerrero Jr., who has absolutely dominated Littell in the two’s previous encounters.

In eight career at-bats (AB) versus the Nats’ righty, Vladdy has recorded four hits, with one of those being a home run.

In addition to his .500 AVG versus Littell, Vladdy has drawn four walks as well, which conveys some elite discipline at the plate.

According to BARTOLO, a new statistical baseball model generated by the Action Network’s Sean Zerillo, Littell heavily relies on his four-seam fastball to retire opposing hitters, which happens to be Vladdy Jr’s second-favorite pitch to hit behind a sinker.

Yet, a deeper look beyond the surface conveys that his heater has been largely ineffective despite his throwing that pitch at a 26.9% clip, as hitters are generating a concerning .414 ‘XWOBA’ (Expected Weighted On-Base Average).

Like Littell’s heater, his sinker (14.9% Usage) has generated extremely low whiff-rates (WHF%) and strikeout-rates (K%) of 12% / 6%, respectively. Also, opposing hitters have recorded a .454 ‘XWOBA’ versus Littell’s sinker in 2026 thus far.

I absolutely love Vladdy Jr. to thrive at the plate on Wednesday afternoon, and will be betting on the Jays’ slugger to exceed both his 1.5 total bases and 1.5 HRR (Hit + Runs + RBIs) marks, which will be my primary betting angles prior to this game.

For a final pick, I favor targeting Nats’ lefty slugger C.J. Abrams, who is undoubtedly the hottest hitter in all of baseball heading into Wednesday’s slate.

While the Blue Jays’ Yesavage generates high spin and heavy swing-and-miss metrics that often test aggressive hitters, C.J. exhibits elite production (.570 SLG%) and plate coverage, which make him very well-suited to handle right-handed velocity and spin profiles when Toronto’s right-hander leaves pitches elevated in the zone.

Yesavage has also been quite vulnerable to the “longball” lately, having given up three homers across his last 10 frames on the mound, which should present a prime opportunity for Abrams, who has smashed seven homers across the Nationals’ last eight games.

That said, I feel great riding C.J. to exceed his 1.5 total bases mark today, building upon his phenomenal recent form at the plate.

Pick: Vladimir Guerrero Jr. Over 1.5 Hits +Runs+RBI | Vladimir Guerrero Jr. Over 1.5 Total Bases | C.J. Abrams Over 1.5 Total Bases


Blue Jays vs Nationals Weather


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About the Author

Ryan graduated from Providence College in 2016 with Bachelor Degrees in Business Economics & Mathematics. It was at Providence where Ryan really first found his passion for sports betting. For a lifelong sports fan with a knack for statistical analysis, he was instantly drawn to the fundamentals of the industry, specifically how sports betting markets functioned and fluctuated. In what primarily started as a recreational hobby, Ryan began studying the ins-and-outs of sports betting markets on a daily basis. He took to Twitter (now X), where he amassed a following for writing a sports betting blog that provided statistical analysis behind his wagers. In spite of seeking employment opportunities elsewhere post graduation, Ryan continued to follow his passion for the statistical analysis of sports betting wagers, eventually deciding to pursue a career in the sports betting industry.

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