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Nationals vs Padres Prediction, Pick, MLB Odds for Tuesday, September 8

Nationals vs Padres Prediction, Pick, MLB Odds for Tuesday, September 8 article feature image
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Denis Poroy-Imagn Images. Pictured: Jackson Merrill and Fernando Tatis Jr.

The San Diego Padres host the Washington Nationals on September 8, 2026. First pitch from Petco Park is scheduled for 9:40 p.m. EDT. The game will be broadcast on NATS.

The Padres are favored by -190 on the moneyline and by -1.5 on the run line. The Nationals are +160 on the moneyline and +1.5 on the run line. The total is set at 8 runs.

Find my MLB picks and Nationals vs Padres prediction below, as well as probable pitchers, weather report, and more.


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Nationals vs Padres Prediction

  • Nationals vs Padres Pick: Jackson Merrill Over 0.5 Walks (+227 or Better)

My Nationals vs Padres best bet is a prop pick on the San Diego center fielder. Make sure to find the best odds by checking our live MLB odds page.


Nationals vs Padres Odds

Nationals Logo
Tuesday, Sep 8
9:40 p.m. ET
NATS
Padres Logo
Nationals Odds
SpreadTotalMoneyline
+1.5
-150
8
-105o / -115u
+160
Padres Odds
SpreadTotalMoneyline
-1.5
+125
8
-105o / -115u
-190
Odds via bet365. Get up-to-the-minute MLB odds here.
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  • Nationals vs Padres moneyline: Nationals +160, Padres -190
  • Nationals vs Padres over/under: 8 (-105o / -115u)
  • Nationals vs Padres spread: Padres -1.5 (+125 ), Nationals +1.5 (-150)

Nationals vs Padres Probable Pitchers

Riley Cornelio (RHP, WAS)StatCasey Mize (RHP, SDP)
2-2W-L5-9
-0.1fWAR (FanGraphs)2.7
5.96 / 4.15ERA / xERA3.64 / 3.45
4.99 / 5.84FIP / xFIP3.61 / 4.30
1.9%K-BB%15.5%
37.7%GB%31.7%
.295BABIP.268
104Stuff+88
82Location+108

Nationals vs Padres MLB Betting Preview

By Derek Carty

With Kevin Cornelio taking the mound for the Nationals and Casey Mize getting the nod for San Diego, I’m locking in a hitter prop on the Padres' side today.

I’m targeting Jackson Merrill to draw a walk at +290 on bet365. If you're shopping around, DraftKings is sitting at +222, and I like this play all the way down to +106.

This isn't about narrative or a hyper-specific matchup edge — it’s purely a numbers play. When THE BAT X projection system identifies a blatant pricing discrepancy relative to the actual probability, you don't overthink it. You just trust the model and take the value.

At +290, the market is simply mispricing Merrill's chances of taking a free pass today. Trust the numbers over time, take the misprice, and let the long-term math work in your favor.

Pick: Jackson Merrill Over 0.5 Walks (+227 or Better)


Nationals vs Padres Weather


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