Colts vs. Titans Odds & Betting Predictions - September 21, 2025

Tailing @Bet_Labs

Smaller since the injuries are potentially lethal especially Sweat and entire right side of OL but can’t pass a 6.

Projection: 0.82 TDs, -233. For more, check out the Fantasy Life player projections.

Adding a half unit here. Also like Warren to lead the game in receiving.

Tailing @The_Oddsmaker

#Tailing @The_Oddsmaker

Lockett has just 2 catches for 9 yards through two games, and it looks like the decline we saw late in his Seahawks career has carried into Tennessee. Rookie Chimere Dike cut into his role last week, dropping his routes-run rate to 46%. I expect that to creep back toward 50–60% this week, but the Titans clearly want to get Dike more involved, which caps Lockett’s upside. Even if his snap share rebounds, his target rate has been a huge concern. Lockett owns a 7% target rate compared to a 9% expected rate in my model. He can still catch a ball or two underneath, but he hasn’t generated yards after the catch in years, which means he’d likely need a downfield shot to threaten this line. My sim has his average at 14.5, but a median closer to 11.5 yards and 3 yards in a market like this is significantly more valuable than say a CeeDee Lamb yardage prop. Have this around a 59% chance to stay under 14.5. There will be weeks where Lockett pops up and clears a line like this, even with his role in decline. But given the usage trend, it feels like a “sell low” opportunity while the prop market is still hanging numbers in this range.

#SundaySixPack Doing my best @Stuckey2 impression

PTP best bet #2

@BKPicks https://myaction.app/n9oxUJkKLWb

@ChrisRaybon Favorite ATD https://myaction.app/InPuWjTELWb

@sundaysixpack @ChrisRaybon https://myaction.app/4MflgQZkKWb

@ChrisRaybon 2 https://myaction.app/4MflgQZkKWb

Novig price

Have this at 39.9. Colts' offense has shredded but now moves outdoors to face a Titans defense that has been good enough so far.

Bet105 bit.ly/boomerh1