Saints vs. Seahawks Odds & Betting Predictions - September 21, 2025

Saints at Seahawks

8:05 pm • CBS

MatchupOpenSpreadTotalMoneyline
Saints 0-0	N/A	N/A	+220
Seahawks 0-0	N/A	N/A	-270

Sunday 8:05 p.m.

September 21, 2025

Lumen FieldSeattle

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No props found

	overall	home	away	favorite	underdog
Seahawks	N/A	N/A	N/A	N/A	N/A
Saints	N/A	N/A	N/A	N/A	N/A

	overall	home o/u	away o/u	favorite o/u	underdog o/u
Seahawks	N/A	N/A	N/A	N/A	N/A
Saints	N/A	N/A	N/A	N/A	N/A

	overall	home	away	favorite	underdog
Seahawks	N/A	N/A	N/A	N/A	N/A
Saints	N/A	N/A	N/A	N/A	N/A

date	opponent	score	spread	over/under	moneyline
Aug 23rd	@GB	L 7-20	+3 L	U 37.5	GB +140
Aug 16th	KC	W 33-16	-5 W	O 38	SEA -220
Aug 8th	LV	W 23-23	+5.5 W	O 36.5	LV +200
Jan 5th	@LA	W 30-25	-7.5 L	O 38.5	SEA -350
Dec 27th	@CHI	W 6-3	-4.5 L	U 42.5	SEA -225

	Starter	2ND	3RD	4TH
QB	Sam Darnold	Drew Lock	Jalen Milroe
RB	Kenneth Walker	Zach Charbonnet	George Holani
WR	Cooper Kupp	Dareke Young
TE	AJ Barner	Elijah Arroyo	Eric Saubert	Nick Kallerup
LT	Charles Cross
LG	Grey Zabel	Bryce Cabeldue
C	Olu Oluwatimi	Jalen Sundell
RG	Anthony Bradford	Christian Haynes	Mason Richman
RT	Abraham Lucas	Josh Jones
LDE	DeMarcus Lawrence	Derick Hall	Jared Ivey	Connor O'Toole
RDE	Leonard Williams	Mike Morris
WLB	Tyrice Knight
MLB	Ernest Jones	Drake Thomas
LCB	Josh Jobe	Nehemiah Pritchett
SS	Julian Love	Nick Emmanwori
FS	Coby Bryant	D'Anthony Bell	Ty Okada
RCB	Riq Woolen	Shaquill Griffin
P	Michael Dickson
H	Michael Dickson
PR	Tory Horton
KR	Tory Horton	Zach Charbonnet
LS	Chris Stoll
DT	Jarran Reed	Rylie Mills
RWR	Tory Horton
NT	Byron Murphy	Johnathan Hankins
K	Jason Myers
LWR	Jaxon Smith-Njigba	Jake Bobo	Cody White
NB	Devon Witherspoon
FB	Robbie Ouzts	Brady Russell
LOLB	Uchenna Nwosu	Boye Mafe
ROLB	Connor O'Toole

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MatchupOverUnder
Saints 0-0	N/A	N/A
Seahawks 0-0	N/A	N/A