Saints vs. Seahawks Odds & Betting Predictions - September 21, 2025
Saints at Seahawks
8:05 pm • CBSSaints at Seahawks Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
 Saints 2-5 | +7.5-118 | o41.5-111 | +310 | |
 Seahawks 3-3 | -7.5-102 | u41.5-110 | -390 | |
Lumen FieldSeattle, WA
Saints vs. Seahawks Expert Picks
Matt Moore
Last 30d: 49-51-3 (+1.6u)
NO +7+100
1.1u
Tyler Shoemaker
Last 30d: 29-32-0 (-0.1u)
NO +7.5-110
5.5u
Kody Malstrom
Last 30d: 72-60-2 (+2.0u)
NO +7.5-110
0.55u
Matthew Freedman
Last 30d: 0-0-0 (+0.0u)
R.Shaheed Anytime TD Scorer Yes+365
0.5u
Projection: +330. For more, check out the Fantasy Life player projections.
S.Darnold o0.5 Int+110
1u
Projection: -155. For more, check out the Fantasy Life player projections.
NO +7.5-115
1.15u
Projection: +7. For more, check out the Fantasy Life game model.
Sean Koerner🔮
Last 30d: 55-68-0 (+1.5u)
G.Holani o16.5 Rush Yds-120
0.5u
Holani should take over most of the Charbs role, but I do expect them to lean even more on KW3. Still, he’s popping in our prop tool because some sites are offering props on him now, this number is too low (would proj his median closer to 24.5 or so). I’m +23 vs ECR on FantasyPros and think the market in general is overlooking him here.
Matt DiLeo
Last 30d: 31-31-0 (-1.9u)
A.Kamara o3.5 Recs-132
1u
Ryan Minion
Last 30d: 249-234-3 (+27.2u)
J.Smith-Njigba o66.5 Rec Yds-110
$1.00
J.Smith-Njigba Anytime TD Scorer Yes+120
$1.20
SEA -3.5 (1H)-118
$1.00
J.Smith-Njigba o6.5 Recs+100
$1.00
A.Kamara o3.5 Recs-130
$1.30
A.Kamara Anytime TD Scorer Yes+125
$1.00
OldSchool0909
Last 30d: 51-59-1 (-3.4u)
SEA -7.5-105
0.95u
Collin Whitchurch
Last 30d: 118-167-3 (-0.0u)
G.Holani o16.5 Rush Yds-120
0.5u
Chris Gimino
Last 30d: 6-7-0 (-0.6u)
G.Holani o4.5 Rush Att+100
2u
K.Walker u19.5 Rush Att-110
0.91u
RoyalsProps
Last 30d: 35-48-2 (-19.3u)
A.Kamara o3.5 Recs-118
1.18u
FD
Gilles Gallant
Last 30d: 26-67-1 (-1.7u)
J.Johnson Anytime TD Scorer Yes+370
1u
Greg Matherne
Last 30d: 22-28-1 (-5.5u)
NO +7.5-110
0.55u
Allan Lem
Last 30d: 48-36-1 (+1.7u)
K.Walker u19.5 Rush Att-110
0.5u
Tailing @chrisgimino_. RG projections have him closer to 15.5 rush attempts assuming we don’t see Walker be a complete bell cow with Zach Charbonnet doubtful, which I tend to agree with.
Topper
Last 30d: 160-148-8 (+5.3u)
Under 42.5-110
1u
NO +7.5-115
1u
Action Pod NFL Picks
Last 30d: 46-128-1 (-12.2u)
Under 41.5-110
1u
@Stuckey2 Favorite Total https://myaction.app/InPuWjTELWb
Mjaybrod
Last 30d: 57-78-1 (-23.1u)
Under 42-110
1u
Nasty stinker
Cam Is Money
Last 30d: 0-0-0 (+0.0u)
NO +7.5-115
1u
A.Kamara o3.5 Recs-125
1u
💰🦡 Jake
Last 30d: 101-111-1 (+21.9u)
Over 41.5-108
1u
New Owner
Last 30d: 0-0-0 (+0.0u)
NO +7.5-101
1u
The Propfessor
Last 30d: 0-0-0 (+0.0u)
A.Kamara o3.5 Recs-140
1u
ThatGuyBets
Last 30d: 0-0-0 (+0.0u)
K.Walker o52.5 Rush Yds-114
1u
Saints vs. Seahawks Previews & Analysis
Saints vs. Seahawks Props
Prop Projections
There are no prop projections found for the selected slate. Please check back later.
Prop Odds Comparison
Line Movement Tracker
Saints vs. Seahawks Public Betting Percentages
Betting Trends
- Seahawks are 3-2 in their last 5 games.
- Seahawks are 1-3 in their last 5 games against the spread
- Seahawks are 1-2 in their road games against the spread
- The totals have gone OVER in 2 of Seahawks' last 5 games
- The totals have gone OVER in 2 of Seahawks' 3 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Saints vs. Seahawks Injury Updates
Saints Injuries
- Travis EtienneRB
Etienne is out with hamstring
Out
- Jordyn TysonWR
Tyson is out with hamstring
Out
Seahawks Injuries
- Zach CharbonnetRB
Charbonnet is out with knee
Out
- Elijah ArroyoTE
Arroyo is out with shoulder
Out
- Jadarian PriceRB
Price is out with chest
Out
Team Stats
Saints vs. Seahawks Odds Comparison
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Saints at Seahawks Team Totals
MatchupOverUnder | ||
|---|---|---|
Saints 2-5 | N/A | N/A |
Seahawks 3-3 | N/A | N/A |