Titans vs. Colts Odds & Betting Predictions - October 26, 2025
Titans at Colts
8:25 pm • CBSTitans at Colts Odds
Spread, Total, Moneyline
MatchupOpenSpreadTotalMoneyline | ||||
|---|---|---|---|---|
Titans 1-6 | +3.5 | +15-110 | o47.5-117 | +900 |
Colts 6-1 | u44.5 | -15-110 | u47.5-108 | -1510 |

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Titans vs. Colts Expert Picks
Matt DiLeo
Last 30d: 41-32-0 (+3.7u)
C.Ward o207.5 Pass Yds-112
1u
D.Jones u30.5 Pass Att-130
1u
Derek Carty
Last 30d: 22-24-0 (+3.1u)
A.Abdullah u3.5 Rush Att-115
1.15u
There may be some value on the rush attempts prop for Ameer Abdullah. THE BLITZ is projecting him to record 0.80 rush attempts, and the oddsmakers are implying 3.79. The model believes there is a 86% chance he records fewer than 3.5 rush attempts. If you can get the under at -116 or better, there is some great value here. (This play is good down to at least -299.) Love THE BLITZ? Get all of Carty’s sports betting projections at EV Analytics: https://evanalytics.com/products/nfl-premium-subscription?ref=zdlkmgz
Brian Bitler
Last 30d: 75-67-2 (+12.0u)
TEN +14.5-102
3u
RocketPlays
Last 30d: 28-51-0 (+2.8u)
A.Pierce o19.5 Longest Reception-115
1u
Gilles Gallant
Last 30d: 28-75-1 (-7.7u)
D.Jones 2+ TDs Yes+2800
0.1u
TD 🪜🪜
Babs .
Last 30d: 96-100-3 (+0.4u)
A.Abdullah o0.5 Recs-120
1u
Nick Giffen
Last 30d: 37-65-1 (+0.8u)
C.Ward o34.5 Pass Att-109
1.09u
Cam Ward over 34.5 Pass Att (-109 at DK ... there's a single 33.5 -130 at MGM but most of the market is at 34.5 so I'll track it at that)
Ward's median is 34 this year, but the Titans are 14.5-point dogs to the Colts here so we can expect more than 34 as a starting point here.
The Colts actually have a below average time of possession, especially compared to the opponents TEN has faced this year, so there will likley be more time TEN spends with the ball
That's in part thanks to the Colts extreme explosiveness with Jonathan Taylor on the ground and several big plays through the air
Colts project as the most explosive team overall in Week 8
The Colts have also made a ton of big defensive plays (6th most turnovers forced per game) to leave them with short fields or even defensive scores, handing the ball back to their opponent quickly
I'm projecting closer to 36 pass attempts with upside for around 39
Brandon Anderson
Last 30d: 46-75-0 (+3.8u)
TEN +900
0.25u
It would be tough to find two teams going in more opposite directions, and that explains one of the biggest spreads of the season thus far, with the Colts favored by two touchdowns.
Indianapolis has the league's best offense. The Colts rank first in Offensive DVOA, tops both rushing and passing. The Titans offense? It ranks dead last in that metric.
Tennessee's defense has been slightly better — can't be worse! — but might be headed in the wrong direction thanks to a couple key injuries. DT Jeffrey Simmons has played like a DPOY contender even on a miserable team. His absence along with CB L'Jarius Sneed leave this defense badly lacking in talent.
They weren't very good to start with. The Titans have allowed 27.4 PPG, even with that pair healthy, and that includes a season-high 41 to the Colts in a blowout Week 3 loss.
The Colts offense has scored at least 29 points in all but one game this season, with games of 29, 31, 33, 38, 40, and 41 points.
That's all we need to know to back Indy's team total over 30.5 points (-109, BetRivers), and we can take a small escalator and go over 34.5 points at +180 (DraftKings) and over 39.5 at +375 (bet365).
Okay, ready for the crazy part?
If the Colts don't go over the team total, something has gone wrong — and maybe the Titans steal this. It sounds crazy now, but since 2018, moneyline underdogs between +750 and +1000 are 4-14 straight up. That doesn't sound great, but if you just blindly bet the long-shot underdog in those spots, you're sitting on a 106% ROI.
Those teams either get blown out or pull a shocker, and these rivals had played eight straight single-digit games before the Week 3 blowout. I think this spread is inflated and would make it closer to -11.5, which would typically mean a moneyline around +450. We're getting twice the payout so let's nibble a Titans ML at +900 (ESPN Bet) and hope we either get a shocking upset or a Colts blowout.
IND o39.5 Team Total+375
0.1u
It would be tough to find two teams going in more opposite directions, and that explains one of the biggest spreads of the season thus far, with the Colts favored by two touchdowns.
Indianapolis has the league's best offense. The Colts rank first in Offensive DVOA, tops both rushing and passing. The Titans offense? It ranks dead last in that metric.
Tennessee's defense has been slightly better — can't be worse! — but might be headed in the wrong direction thanks to a couple key injuries. DT Jeffrey Simmons has played like a DPOY contender even on a miserable team. His absence along with CB L'Jarius Sneed leave this defense badly lacking in talent.
They weren't very good to start with. The Titans have allowed 27.4 PPG, even with that pair healthy, and that includes a season-high 41 to the Colts in a blowout Week 3 loss.
The Colts offense has scored at least 29 points in all but one game this season, with games of 29, 31, 33, 38, 40, and 41 points.
That's all we need to know to back Indy's team total over 30.5 points (-109, BetRivers), and we can take a small escalator and go over 34.5 points at +180 (DraftKings) and over 39.5 at +375 (bet365).
Okay, ready for the crazy part?
If the Colts don't go over the team total, something has gone wrong — and maybe the Titans steal this. It sounds crazy now, but since 2018, moneyline underdogs between +750 and +1000 are 4-14 straight up. That doesn't sound great, but if you just blindly bet the long-shot underdog in those spots, you're sitting on a 106% ROI.
Those teams either get blown out or pull a shocker, and these rivals had played eight straight single-digit games before the Week 3 blowout. I think this spread is inflated and would make it closer to -11.5, which would typically mean a moneyline around +450. We're getting twice the payout so let's nibble a Titans ML at +900 (ESPN Bet) and hope we either get a shocking upset or a Colts blowout.
IND o34.5 Team Total+180
0.25u
It would be tough to find two teams going in more opposite directions, and that explains one of the biggest spreads of the season thus far, with the Colts favored by two touchdowns.
Indianapolis has the league's best offense. The Colts rank first in Offensive DVOA, tops both rushing and passing. The Titans offense? It ranks dead last in that metric.
Tennessee's defense has been slightly better — can't be worse! — but might be headed in the wrong direction thanks to a couple key injuries. DT Jeffrey Simmons has played like a DPOY contender even on a miserable team. His absence along with CB L'Jarius Sneed leave this defense badly lacking in talent.
They weren't very good to start with. The Titans have allowed 27.4 PPG, even with that pair healthy, and that includes a season-high 41 to the Colts in a blowout Week 3 loss.
The Colts offense has scored at least 29 points in all but one game this season, with games of 29, 31, 33, 38, 40, and 41 points.
That's all we need to know to back Indy's team total over 30.5 points (-109, BetRivers), and we can take a small escalator and go over 34.5 points at +180 (DraftKings) and over 39.5 at +375 (bet365).
Okay, ready for the crazy part?
If the Colts don't go over the team total, something has gone wrong — and maybe the Titans steal this. It sounds crazy now, but since 2018, moneyline underdogs between +750 and +1000 are 4-14 straight up. That doesn't sound great, but if you just blindly bet the long-shot underdog in those spots, you're sitting on a 106% ROI.
Those teams either get blown out or pull a shocker, and these rivals had played eight straight single-digit games before the Week 3 blowout. I think this spread is inflated and would make it closer to -11.5, which would typically mean a moneyline around +450. We're getting twice the payout so let's nibble a Titans ML at +900 (ESPN Bet) and hope we either get a shocking upset or a Colts blowout.
IND o30.5 Team Total-109
1u
It would be tough to find two teams going in more opposite directions, and that explains one of the biggest spreads of the season thus far, with the Colts favored by two touchdowns.
Indianapolis has the league's best offense. The Colts rank first in Offensive DVOA, tops both rushing and passing. The Titans offense? It ranks dead last in that metric.
Tennessee's defense has been slightly better — can't be worse! — but might be headed in the wrong direction thanks to a couple key injuries. DT Jeffrey Simmons has played like a DPOY contender even on a miserable team. His absence along with CB L'Jarius Sneed leave this defense badly lacking in talent.
They weren't very good to start with. The Titans have allowed 27.4 PPG, even with that pair healthy, and that includes a season-high 41 to the Colts in a blowout Week 3 loss.
The Colts offense has scored at least 29 points in all but one game this season, with games of 29, 31, 33, 38, 40, and 41 points.
That's all we need to know to back Indy's team total over 30.5 points (-109, BetRivers), and we can take a small escalator and go over 34.5 points at +180 (DraftKings) and over 39.5 at +375 (bet365).
Okay, ready for the crazy part?
If the Colts don't go over the team total, something has gone wrong — and maybe the Titans steal this. It sounds crazy now, but since 2018, moneyline underdogs between +750 and +1000 are 4-14 straight up. That doesn't sound great, but if you just blindly bet the long-shot underdog in those spots, you're sitting on a 106% ROI.
Those teams either get blown out or pull a shocker, and these rivals had played eight straight single-digit games before the Week 3 blowout. I think this spread is inflated and would make it closer to -11.5, which would typically mean a moneyline around +450. We're getting twice the payout so let's nibble a Titans ML at +900 (ESPN Bet) and hope we either get a shocking upset or a Colts blowout.
Kyle Murray
Last 30d: 67-64-2 (+6.5u)
C.Ward o1.5 Rush Att-115
1.15u
TAN Pod Touchdown Show
Last 30d: 15-54-1 (-5.8u)
C.Dike Anytime TD Scorer Yes+475
0.5u
@ChrisRaybon https://myaction.app/mVODhIbOJXb
J.Taylor 3+ TDs Yes+600
0.5u
@ChrisRaybon https://myaction.app/mVODhIbOJXb
Action Pod NFL Picks
Last 30d: 59-104-0 (+0.0u)
IND o34.5 Team Total+180
0.56u
@wheatonbrando https://myaction.app/2IsFjc7LJXb
IND o39.5 Team Total+375
0.27u
@wheatonbrando https://myaction.app/2IsFjc7LJXb
TEN +900
0.11u
@wheatonbrando https://myaction.app/2IsFjc7LJXb
IND o30.5 Team Total-109
1u
@wheatonbrando https://myaction.app/2IsFjc7LJXb
Moneyline Hacks
Last 30d: 114-123-2 (+39.5u)
D.Jones o11.5 Rush Yds-110
1u
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Gilles Gallant
Last 30d: 28-75-1 (-7.7u)
D.Jones Anytime TD Scorer Yes+260
0.5u
Top Shelf Action 🥃
Last 30d: 178-156-0 (-0.3u)
C.Ward o198.5 Pass Yds-115
0.8u
C.Ward o34.5 Pass Att-105
0.6u
Cam Is Money
Last 30d: 73-95-3 (-16.7u)
G.Helm o21.5 Rec Yds-115
1u
Action Pod NFL Picks
Last 30d: 59-104-0 (+0.0u)
C.Dike Anytime TD Scorer Yes+450
0.22u
Favorite ATD @ChrisRaybon https://myaction.app/spVgtW2PHXb
Over 47.5-105
1u
Favorite Total @Stuckey2 https://myaction.app/spVgtW2PHXb
💰🦡 Jake
Last 30d: 116-129-6 (+3.8u)
C.Ridley Anytime TD Scorer Yes+375
0.3u

Chris Raybon
Last 30d: 19-28-0 (-5.3u)
Over 46.5-114
1u
No Simmons, Snead for TEN, IND Vance duo on D but getting WRs Downs and Dillon back.
💰🦡 Jake
Last 30d: 116-129-6 (+3.8u)
C.Ridley Anytime TD Scorer Yes+350
0.1u
Cam Is Money
Last 30d: 73-95-3 (-16.7u)
D.Jones u29.5 Pass Att-114
1u
FTN Fantasy
Last 30d: 48-45-1 (+4.8u)
IND -14-110
1u
Titans vs. Colts Previews & Analysis
Titans vs. Colts Props
Prop Projections
There are no prop projections found for the selected slate. Please check back later.
Prop Odds Comparison
Line Movement Tracker
Titans vs. Colts Public Betting Percentages
Betting Trends
- Colts are 4-1 in their last 5 games.
- Colts are 3-2 in their last 5 games against the spread
- Colts are 2-1 in their road games against the spread
- The totals have gone OVER in 2 of Colts' last 5 games
- The totals have gone OVER in 2 of Colts' 4 last games at home
Matchup History
Against the Spread (ATS) History
Over/Under History
Last 5 Matchups
Colts vs. Titans Injury Updates

Colts Injuries

Titans Injuries
- Calvin RidleyWR
Ridley is out with hamstring
Out
- Kevin WinstonS
Winston is doubtful with hamstring
Doubtful
- Kalel MullingsRB
Mullings is out with ankle
Out
Player Stats
- passing yards
Daniel Jones1790pyds - passing touchdowns
Daniel Jones10ptd - rushing yards
Jonathan Taylor697ryds - rushing touchdowns
Jonathan Taylor10rtd
Depth Charts
| Starter | 2ND | 3RD | 4TH | |||
|---|---|---|---|---|---|---|
| QB | Daniel Jones | Anthony Richardson | Riley Leonard | |||
| RB | Jonathan Taylor | Tyler Goodson | DJ Giddens | Ulysses Bentley | ||
| WR | Josh Downs | Anthony Gould | Coleman Owen | |||
| TE | Tyler Warren | Mo Alie-Cox | Drew Ogletree | Will Mallory | Sean McKeon | Maximilian Mang |
| LT | Bernhard Raimann | Jalen Travis | ||||
| LG | Quenton Nelson | Dalton Tucker | ||||
| C | Tanor Bortolini | Danny Pinter | ||||
| RG | Matt Goncalves | Josh Sills | ||||
| RT | Braden Smith | Luke Tenuta | ||||
| LDE | Kwity Paye | Tyquan Lewis | JT Tuimoloau | |||
| RDE | Laiatu Latu | Samson Ebukam | Durell Nchami | |||
| WLB | Jaylon Carlies | Austin Ajiake | ||||
| MLB | Zaire Franklin | Segun Olubi | ||||
| LCB | Charvarius Ward | |||||
| SS | Nick Cross | Daniel Scott | ||||
| FS | Cam Bynum | Rodney Thomas | Trey Washington | |||
| RCB | Jaylon Jones | Johnathan Edwards | ||||
| P | Rigoberto Sanchez | |||||
| H | Rigoberto Sanchez | |||||
| PR | Anthony Gould | Josh Downs | Coleman Owen | |||
| KR | Anthony Gould | Ashton Dulin | Tyler Goodson | DJ Giddens | ||
| LS | Luke Rhodes | |||||
| RWR | Alec Pierce | Adonai Mitchell | ||||
| K | Spencer Shrader | |||||
| LWR | Michael Pittman | Ashton Dulin | Laquon Treadwell | |||
| NT | Grover Stewart | Neville Gallimore | Eric Johnson | |||
| DT | DeForest Buckner | Adetomiwa Adebawore | Tim Smith | |||
| NB | Kenny Moore | Chris Lammons |
Team Stats
1119
YDS
1751
136/236
Comps/Atts
153/217
5.746
YPA
8.29
4/5
TDs/INTs
10/3
30/237
Sacks/Yards
6/48
Titans vs. Colts Odds Comparison
Could not load odds
Titans at Colts Team Totals
MatchupOverUnder | ||
|---|---|---|
Titans 1-6 | N/A | N/A |
Colts 6-1 | N/A | N/A |




