The Philadelphia Eagles (11-6) host the San Francisco 49ers (12-5) today at Lincoln Financial Field in Philadelphia, Pa. Kickoff is scheduled for 4:30 p.m. ET. 49ers vs Eagles will broadcast on FOX.
49ers vs Eagles odds list the Eagles as -245 moneyline favorites and 49ers as +200 underdogs. The game total is 44 (-112o / -108u). The Eagles are 5.5-point favorites on the spread (Eagles -5.5; -109).
Below, you can find 49ers vs Eagles picks for the spread and props for Jalen Hurts, George Kittle and Jauan Jennings.
49ers vs Eagles Picks & Props
| Game | Time (ET) | Best Bet |
|---|---|---|
| 4:30 p.m. | ||
| 4:30 p.m. | ||
| 4:30 p.m. | ||
| 4:30 p.m. | ||
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NFL Odds page, which automatically surfaces the best lines for every game. | ||
49ers vs Eagles Odds
| 49ers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+5.5 -112 | 44 -112o / -108u | +200 |
| Eagles Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-5.5 -109 | 44 -112o / -108u | -245 |
NFL odds for the Wild Card Round via bet365
49ers vs Eagles Against the Spread Prediction
By Billy Ward
I’m on the Eagles for their wild card matchup against the 49ers, but it’s hard to see why this line has moved as much as it has.
Philadelphia opened as a 3.5-point favorite, but the line has shifted towards them all week, with some books going as high as 6.5 at the time of this writing. That’s despite relatively positive injury news for the 49ers, who got two limited practices out of star left tackle Trent Williams.
Sure, Ricky Pearsall is likely to miss the game. However, it’s hard to see even the best receivers in the NFL being worth a field goal to the spread, and Pearsall, with all due respect, isn’t in that group.
Personally, I prefer to wait to bet this line to see if it moves even higher (or we get a better price on the 6.5) but I’ll be on the 49ers spread at the best line possible.
Pick: 49ers +6.5 (-115)
George Kittle Player Props: Receiving Yards
By Brit Devine
George Kittle is going to be one of the main focal points of the passing offense for the 49ers, but even so, it should be very tough for him to have a big game.
The Eagles allowed the fifth-fewest targets, second-fewest receptions, and second-fewest yards to tight ends this season. They allowed just one TE to go over this line all season, and that was Travis Kelce with 61 yards in Week 2. This is largely due to the Eagles having two of the better pass-coverage LBs in the league — Zack Baun and Jihaad Campbell.
Kittle has the ability to have a big game, but the 49ers would be wise to be game-planning elsewhere for this one.
Pick: George Kittle Under 60.5 Receiving Yards (-110)
Jauan Jennings Anytime Touchdown Pick
Last week, Jauan Jennings finally had a game where he didn't score a touchdown — but the entire offense didn't have a TD either.
I'm going right back to the well here.
Jennings has nine TDs in the last 10 weeks, and somehow, we are getting +250 odds. He's potentially the best red-zone threat the 49ers have outside of Christian McCaffrey.
The Eagles defense is good, but we've seen the 49ers put up massive offensive totals every week (outside of last week). I have the true odds here under +200.
Pick: Jauan Jennings Anytime Touchdown Scorer (+260)
Jalen Hurts Props: Rush Attempts
By Sean Koerner
Jalen Hurts hasn’t been using his legs as much this season and, while that could obviously change now that we’re in the playoffs, I still think there’s decent value on his under on rush attempts.
Hurts has only cleared this once since Week 5, and part of that is because he’s averaging a career-low 1.7 designed rush attempts per game this season. The league has started to make it tougher to run the infamous tush push by calling false starts on it at a higher rate, and the play itself hasn’t been as efficient this year.
We’ve also seen the Eagles experiment with variations, like pitching the ball to Barkley instead, which led to a long TD run against the Chargers. As a result, we haven’t seen Hurts rack up as many cheap rush attempts.
Hurts is facing a 49ers defense that’s struggled to generate pressure since Nick Bosa went down in Week 3; they’ve generated the second-lowest pressure rate since then. Lane Johnson is tentatively expected to return as well, so Hurts could operate from one of the cleanest pockets he’s seen all season, which would lower his expected scramble rate.
Hurts' rush attempts prop has crept up with the Eagles now favored by six points over the 49ers (it was -3.5 earlier in the week), which makes sense because his chances of kneel-downs from a victory formation increase, which is always key to this market. But a leading game script would also lower his dropback volume and potential scrambles, which caps his ceiling here.
I’m projecting Hurts closer to 6.7 rush attempts, and having access to a win if he lands on seven exactly (which I have happening around 15% of the time) is massive. That’s why I’m projecting around a 63% chance he stays under 7.5.
Pick: Jalen Hurts Under 7.5 Rush Attempts (-130)






















