The Buffalo Bills (7-1) take on the New York Jets (2-7) today in NFL Week 10. Kickoff is set for 1:00 p.m. ET from MetLife Stadium in East Rutherford, N.J. The game will broadcast live on CBS.
The Bills are 8.5-point favorites over the Jets on the spread, with the over/under set at 50.5 total points. Buffalo is a -440 moneyline favorite while New York is a +340 underdog.
Let's get into my Bills vs Jets predictions for Sunday, November 15.
- Bills vs Jets pick: Jets +8.5 (-112)
My Bills vs. Jets best bet is New York to cover the spread, with the best price currently available at DraftKings. Make sure to find the best odds by checking our live NFL odds page.
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Bills vs Jets Odds
| Bills Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-8.5 -108 | 50.5 -118o / -102u | -440 |
| Jets Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+8.5 -112 | 50.5 -118o / -102u | +340 |
- Bills vs Jets Spread: Bills -8.5, Jets +8.5
- Bills vs Jets Total: 50.5
- Bills vs Jets Moneyline: Bills -440, Jets +340
Bills vs Jets NFL Week 10 Preview
If you consult virtually any trusted power rating, the Bills sit near the absolute top of the NFL.
However, digging into the margins paints a very different picture of the Bills. According to Nick Giffen's NFL Luck Rankings, Buffalo currently profiles as the second-luckiest team in the league.
The Bills are also stepping into a difficult scheduling spot, operating on short rest after their offense spent 42 minutes on the field against the Vikings on Monday Night Football.
When you look closely at Josh Allen, there are clear avenues to frustrate him. He routinely bails out the Bills, but a rested, aggressive defense can force him into making mistakes.
On the opposite end of the variance spectrum, the Jets rank as the second-unluckiest team in the NFL.
Looking at deserved margins, the Jets have had four separate games stolen from them this season — the most of any team in the league.
Fortunately, the tide appears to be turning from a health and personnel standpoint. The Jets are finally getting guard Dylan Parham back on the offensive line, which is a massive upgrade for Geno Smith's protection. Additionally, wide receivers Garrett Wilson and Omar Cooper Jr. are expected to suit up.
The Jets also made a savvy move by trading Andre Cisco at the trade deadline and inserting Dane Belton at safety, which instantly improves their tackling and run support on the back end — a vital upgrade when facing Buffalo.
Bills vs Jets Prediction, Betting Analysis
The historical trends all point toward fading big road favorites in these spots.
Since 2020, there have been 78 teams that closed as a road favorite of more than one possession (8.5 points or higher). Those teams are an abysmal 29-48-1 against the spread (37%).
With the Jets finally getting their premium offensive weapons back, they should be a good bet to keep this inside the large number.
Pick: Jets +8.5 (-112)

















