The Carolina Panthers (3-5) and New Orleans Saints (3-5) will face off in NFL Week 10. Kickoff is set for 1:00 p.m. ET from Caesars Superdome in New Orleans, La. The game will broadcast live on FOX.
The Saints are 1.5-point favorites over the Panthers on the spread, with the over/under set at 48.5 total points. New Orleans is a -138 moneyline favorite and Carolina is a +118 underdog.
Let's get into my Panthers vs Saints predictions for today's NFC South showdown.
Panthers vs Saints Prediction
- Panthers vs Saints pick: Panthers +3 (-120)
My Panthers vs. Saints best bet is Carolina to cover the spread. Make sure to find the best odds by checking our live NFL odds page.
If you want more Action Network content, add us as a preferred source on Google and download the Action Network app for more NFL picks and analysis!
Panthers vs Saints Odds
| Panthers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +100 | 48.5 -115o / -105u | +118 |
| Saints Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -120 | 48.5 -115o / -105u | -138 |
- Panthers vs Saints Spread: Panthers +1.5, Saints -1.5
- Panthers vs Saints Total: 48.5
- Panthers vs Saints Moneyline: Panthers +118, Saints -138
Panthers vs Saints NFL Week 10 Preview
Carolina Panthers Betting Preview
The Panthers are getting some desperately needed reinforcements on the defensive side of the ball.
Carolina's secondary has been depleted recently, but it looks like starting cornerback Will Lee III could return — though Mike Jackson is listed as doubtful. Linebacker Jaelan Phillips is also questionable after practicing all week.
Getting healthy on the defensive side of the ball is huge for the Panthers as it's where they've really struggled of late.
Offensively, Carolina's primary focus will be establishing the ground game, and it matches up well here because the New Orleans defensive front has been incredibly generous against the run.
While the Panthers' run defense remains a liability, they are facing a Saints team that is incapable of running the football, neutralizing Carolina's biggest weakness.
New Orleans Saints Betting Preview
The Saints offense is currently operating on inflated, unsustainable red-zone metrics.
The Saints have scored touchdowns on 70% of their drives that reached the red zone this season, which is an anomaly — especially for a team that doesn't possess a reliable rushing attack. The ground game is so bad that Tyler Shough leads the team in rushing yards (162).
Regression is looming for this New Orleans offensive unit.
While the Saints took some respected professional money last week and benefited from the Browns completely self-destructing with goal-line fumbles and punt return disasters, I am not sold on New Orleans' baseline efficiency.
The Saints are laying nearly a full field goal in a divisional game against a team that matches up well schematically, and I just can't get behind that.
Panthers vs Saints Prediction, Betting Analysis
The Panthers are getting healthier on the defensive side of the ball, and they are facing a Saints offense due for some red-zone regression.
This is my favorite teaser leg of the week to push Carolina up through the key numbers. But ultimately, I like the Panthers +3 here too.
Pick: Panthers +3 (-120)
