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The Los Angeles Chargers (0-5) and Kansas City Chiefs (4-0) will clash in Week 6 of the NFL season this afternoon. Kickoff is set for 4:25 p.m. ET from GEHA Field at Arrowhead Stadium in Kansas City, Mo. The game will broadcast live on CBS.
The Chiefs are 7.5-point favorites over the Chargers on the spread, with the over/under set at 41.5 points. Kansas City is a -390 moneyline favorite to win outright, while Los Angeles is a +310 underdog.
Let's get into my Chargers vs Chiefs predictions for today's AFC West showdown.
- Chargers vs Chiefs pick: Over 41.5 (-108)
My Chargers vs. Chiefs best bet is the total to go Over 42.5 points, with the best price currently available at FanDuel. Make sure to find the best odds by checking our live NFL odds page.
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Chargers vs Chiefs Odds
| Chargers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+7.5 -115 | 41.5 -110o / -110u | +310 |
| Chiefs Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-7.5 -105 | 41.5 -110o / -110u | -390 |
- Chargers vs Chiefs spread: Chargers +7.5, Chiefs -7.5
- Chargers vs Chiefs total: over/under 41.5
- Chargers vs Chiefs moneyline: Chargers +310, Chiefs -390
Chargers vs Chiefs NFL Week 6 Preview
The Chargers are a completely defeated and lost football team, a far cry from what everyone expected headed into the new season. It's so bad that they are finding new ways to blow covers every single week in the fourth quarter.
The Bolts defense is constantly backed against the wall — they have allowed an astounding 18 opponent drives to start in plus-territory this year (the next-closest team is at 11).
Offensively, Justin Herbert has been the worst quarterback in the league against the blitz mainly because all of his receivers are hurt, and he was forced to play behind four rookie offensive linemen last week.
The Chiefs are fresh off a bye week, giving head coach Andy Reid and defensive coordinator Steve Spagnuolo extended prep time to beat up on the Chargers.
Kansas City's offense looks better with each passing week. The Chiefs have established a legitimate running game with Kenneth Walker III, they are utilizing more under-center looks, and Patrick Mahomes is finding his rhythm.
Spagnuolo is going to dial up relentless blitzes against an overwhelmed Chargers offensive line that has been incapable of protecting Herbert.
Chargers vs Chiefs Prediction, Betting Analysis
Sharps are already hammering this Over, and it makes total sense.
The Chargers routinely gift opponents excellent field position by turning the ball over in plus territory, which provides an easy path to points for Patrick Mahomes and the Chiefs.
Expect a high-scoring affair driven by Kansas City consistently capitalizing on Los Angeles' mistakes.
Pick: Over 41.5 (-110)

















