Our football staff is focused on six of Sunday's biggest games for our NFL predictions in Week 11 on November 16.
First, we'll target Packers vs Giants and Bears vs Vikings in the early window. Later in the afternoon, we have a pair of picks for Seahawks vs Rams and Ravens vs Browns. We also have picks for Bengals vs Steelers, Buccaneers vs Bills and more.
Let's dive into our expert NFL picks and best bets for the Week 11 Sunday slate.
NFL Predictions & Picks — Week 11
| Game | Time (ET) | Pick |
|---|---|---|
  | 1:00 p.m. | |
  | 1:00 p.m. | |
  | 1:00 p.m. | |
  | 1:00 p.m. | |
  | 4:05 p.m. | |
  | 4:25 p.m. | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our NFL Odds page, which automatically surfaces the best lines for every game. | ||
Packers vs Giants
The Giants offense ranks 14th in yards per game at about 333, showing consistent production.
Their rushing attack averages 123 yards per game, which is 11th-best in the league and allows them to sustain drives and control tempo.
The Packers defense is solid both against the run and pass, which makes covering a touchdown spread challenging, but the Giants have been effective at protecting the football and generating efficient drives without relying on big plays.
With the spread at +7, the Giants’ ability to stay methodical and avoid critical mistakes gives them a realistic path to remain within one score.
Also, who can resist some Jameis Winston magic?
Pick: Giants +7 (-110)
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Bears vs Vikings
By Dylan Wilkerson
The Bears are averaging 380 yards and 27 points per game this season. Their defense has been opportunistic recently, forcing turnovers at key moments.
The Vikings offense has struggled in key areas, ranking 31st in 3rd‑down conversion and 20th in red-zone efficiency, which could limit sustained drives.
In recent head-to-head matchups, Chicago has kept games close, losing by single digits in two of its last three meetings.
With the spread at +3, Chicago has the offensive production and favorable matchup dynamics to stay within one score and cover.
Pick: Bears +3 (-118)
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Bengals vs Steelers
By Bet Labs
The NFL system titled "High Winds" is built on how weather directly impacts offensive efficiency and scoring potential.
When average wind speeds climb into the double digits, passing games struggle with accuracy, kicking becomes unreliable, and play calling leans more heavily toward conservative runs.
This naturally limits explosive plays and lowers scoring opportunities.
With temperatures sitting in a reasonable range that does not drastically impact player stamina or ball handling, wind becomes the defining variable.
Both regular season and postseason games fit this mold, as weather remains an equalizer regardless of stakes.
Betting the under in these conditions takes advantage of how the market often undervalues the true effect of sustained wind on football outcomes.
Pick: Under 49 (-110)
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Buccaneers vs Bills
By Dylan Wilkerson
The Buccaneers offense, averaging 328 yards per game, has the tools to stay competitive against the Bills.
Buffalo's run defense has struggled this season, allowing 147 rushing yards per game, which ranks 3rd-worst in the league.
This vulnerability gives Tampa Bay a clear path to control the ground game, sustain drives and limit Buffalo’s possessions.
By mixing runs and short passes, Tampa Bay can keep the game close.
With the spread at +6, the Bucs' ability to exploit Buffalo’s run‑defense weaknesses and generate consistent offensive drives gives them a realistic chance to cover.
Pick: Buccaneers +5.5 (-110)
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Seahawks vs Rams
By Bet Labs
The system titled "Great Condition Divisional Road 'Dogs" works on the belief that divisional underdogs traveling in good weather during the early and middle parts of the season carry hidden value.
In the NFL division games are often tighter and more unpredictable because of the familiarity and rivalry factor which narrows the talent gap.
When the visiting team is the 'dog in November (like the Seahawks are in this game against the Rams), conditions are generally stable with limited wind allowing both teams to execute their normal game plans without weather being a major factor.
In these spots the public often overvalues the home side, yet divisional familiarity and the motivational boost of playing a rival make the road 'dog more competitive than the line suggests.
Pick: Seahawks +3 (-110)
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Ravens vs Browns
By Dylan Wilkerson
The Browns have been strong against the run, allowing 97.9 rushing yards per game, which ranks among the better marks in the league this season.
Baltimore excels in converting third downs and scoring drives, but the Browns’ run-stopping ability can limit the Ravens’ tempo and force more predictable passing situations.
Offensively, the Browns average around 17-18 points per game, and with a 7.5-point spread, they only need to keep the game within one score.
The Browns' defensive strength and ability to stay competitive gives them a realistic path to cover against Baltimore.
Pick: Browns +7.5 (-110)
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