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NFL Saturday Odds, Predictions: Bills vs Broncos, 49ers vs Seahawks (Divisional Round)

NFL Saturday Odds, Predictions: Bills vs Broncos, 49ers vs Seahawks (Divisional Round) article feature image
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Matthew Hinton-Imagn Images. Pictured: San Francisco 49ers head coach Kyle Shanahan

The NFL Divisional Round kicks off Saturday, with Bills vs. Broncos at 4:30 p.m. ET (CBS) and followed by 49ers vs. Seahawks at 8 p.m. ET (FOX).

NFL odds for Saturday list Denver as a 1-point spread favorite against Buffalo, and Seattle as a -7.5 favorite against San Francisco.

The sharpest NFL predictions for Saturday come via the Bills vs. Broncos spread; however, it's the 49ers vs. Seahawks over/under that's catching the eyes of the wiseguys in that matchup.

Below, we reveal two NFL predictions that professional bettors are making for Saturday's Divisional Round playoff matchups.

NFL Predictions for Saturday's Divisional Round

*Odds as of Friday afternoon

Bills vs. Broncos Prediction

Let's start with a Bills vs. Broncos spread prediction.