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NFL Odds for Seahawks vs. 49ers: Betting System Pick & Prediction for Saturday’s Spread

NFL Odds for Seahawks vs. 49ers: Betting System Pick & Prediction for Saturday’s Spread article feature image
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Photo by Steph Chambers/Getty Images. Pictured: Head coach Pete Carroll of the Seattle Seahawks

  • Saturday's NFL playoff wild-card action gets underway with the Seattle Seahawks taking on the San Francisco 49ers.
  • Live NFL odds show the 49ers as 9.5-point spread favorites against the Seahawks, with Saturday's over/under sitting at 42.
  • Using our PRO NFL picks, we detail a betting system prediction with a 65% win rate that matches Seahawks vs. 49ers today.

NFL Odds: Seahawks vs. 49ers

Seahawks Odds +9.5
49ers Odds -9.5
Over/Under 42
Date Saturday, Jan. 14
Time 4:30 p.m. ET
Channel FOX

*Odds as of Saturday afternoon

The Seattle Seahawks and San Francisco 49ers will meet for the third time this season with Seattle looking for its first win against its NFC West rivals.

San Francisco topped Seattle, 27-7, back in Week 2, then completed its sweep with a 21-13 victory in Week 15.

The latest NFL odds are suggesting another relatively easy win for the 49ers today, but what does that mean for bettors?

Is the best NFL pick to lay the points with the Niners or bet on the Seahawks to keep this game close?

Or with wet and windy weather in the latest forecast, is the smartest NFL prediction on the Seahawks vs. 49ers over/under instead?

With the help of the Action Network’s PRO betting tools, let’s examine the NFL pick that sharps are making, which also matches a betting system with a 65% against-the-spread (ATS) win rate dating back to 2004.

NFL Pick: Seahawks vs. 49ers

Seahawks vs. 49ers is shaping up as a classic Pros vs. Joes situation.

Sixty-seven percent of spread tickets are laying it with San Francisco to this point, yet the line has dipped from Seattle +10.5 to +9.5 (click here for live NFL odds).