This All-American matchup pits last year's Wimbledon finalist Amanda Anisimova against 2025 Australian Open champion Madison Keys.
Both are looking for their first title in London, but one of those quests will stop short in this third round.
Anisimova won the only match between them so far, and we'll look into the betting value of this second meeting.
Find my Wimbledon preview and Anisimova vs Keys prediction for Saturday below.
Amanda Anisimova vs Madison Keys Player Prediction
- Anisimova vs Keys Pick: Anisimova To Commit More Double Faults / Keys Under 6.5 Aces
My Anisimova vs Keys best bets are on Anisimova to commit more double faults and Keys to hit six aces or fewer. Make sure to find the best odds by checking our live Wimbledon odds page.
Anisimova vs Keys Odds
| Amanda Anisimova Odds | +131 |
| Madison Keys Odds | -167 |
| Spread | Anisimova +2.5 (-125), Keys -2.5 (-115) |
| Over/Under | 22.5 (-120o / -125u) |
| Anisimova-Keys H2H | 1-0 |
| Time | How to Watch | Saturday, Approx. 09:40 a.m. ET | ESPN Unlmtd |
| Odds via DraftKings | |
Anisimova vs Keys Preview, Prediction
By: Tudor Cosma
Amanda Anisimova Betting Preview
Amanda Anisimova hasn’t had the year she hoped for, and some physical issues have held her back. She struggled terribly against Sofia Kenin here, winning 7-6 in the tiebreaker, and today she’ll need to find a different rhythm if she wants to prevail.
Anisimova is having a modest season. There are objective reasons for this — she’s been dealing with some injuries — but her play hasn’t been convincing at nearly any tournament.
As mentioned, she isn’t impressing here either, but Amanda is such a great talent that she can step up her game at any time.
Madison Keys Betting Preview
Madison Keys feels great on grass and is coming off a title at Eastbourne. She is much more careful on her second serve and rarely commits many double faults.
She is an exceptional athlete in her own right, and is last year’s Australian Open champion.
Keys has one of the best serves in the world, but recently she’s been hitting fewer aces than we’re used to, which we'll discuss soon for our betting analysis.
Anisimova vs Keys Predictions, Betting Analysis
Anisimova committed six double faults in her last match. She generally pushes her second serve and is prone to double faults. At Queen’s, in her loss to Jovic, she committed no fewer than 12 double faults without any aces.
Meanwhile, Keys had seven in the first round against Day, which was more of an exception, as it was a long match. Against Swan, she had two. So I will pick Anisimova to commit more double faults in this matchup.
For our second pick, we'll go with aces. In the first round, in a very long match against Day, Keys hit only three aces. Then, against Swan, she also hit three.
We might see a similar number here. I believe Madison will hit fewer than 6.5 aces.
Picks: Anisimova To Commit More Double Faults / Keys Under 6.5 Aces













