Tigers vs. Guardians Odds & Betting Predictions - September 24, 2025

Tigers at Guardians

10:40 pm • FDSDET
1 - 3

Tigers at Guardians Odds

Spread, Total, Moneyline

MatchupOpenSpreadTotalMoneyline
Tigers
85-72
-1.5
+1.5-186
o7.5-115
+119
Guardians
85-72
u8
-1.5+151
u7.5-105
-146
location pinWednesday 10:40 p.m.
September 24, 2025
Progressive FieldCleveland
Tigers vs. Guardians Expert Picks
Boomer Betz
Boomer Betz
Last 30d: 124-115-1 (+9.2u)
DET +118 (Live)
1u
The Degenerates
The Degenerates
Last 30d: 71-76-2 (-12.8u)
CLE -142
1.42u
Wags Wins
Wags Wins
Last 30d: 158-139-1 (+8.1u)
Under 8-119
1.5u
YBK Picks.com
Last 30d: 33-46-0 (-35.2u)
CLE -1+100
2u
Picks Office
Picks Office
Last 30d: 62-87-4 (-21.4u)
CLE -120
1u
Grant Neiffer
Grant Neiffer
Last 30d: 42-145-11 (+1.9u)
R.Greene o0.5 HR+425
0.25u
J.Ramirez o0.5 HR+450
0.25u
Bet Labs
Bet Labs
Last 30d: 22-17-0 (+4.0u)
CLE -153
1.42u
Lines at Lunch
Lines at Lunch
Last 30d: 95-83-2 (+7.9u)
Over 7.5-115
1.15u
Sean Zerillo
Sean Zerillo
Last 30d: 163-171-4 (-3.2u)
Over 7.5-108
0.54u
Bet to -115
Moneyline Hacks
Moneyline Hacks
Last 30d: 110-127-8 (+45.5u)
CLE -121
1u
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Tigers vs. Guardians Previews & Analysis

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    Zerillo's Opening Pitch for Wednesday

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Prop Odds Comparison

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Line Movement Tracker

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Tigers vs. Guardians Public Betting Percentages

Away Logo

Tigers

Public

30%

Bets%

70%

Money%

Matchup History

Against the Spread (ATS) History

overallhomeawayfavoriteunderdog
Guardians
85-7238-3847-3432-3251-38
Tigers
72-8541-4031-4549-6323-20

Over/Under History

overallhome o/uaway o/ufavorite o/uunderdog o/u
Guardians
67-84-635-38-332-46-332-31-134-50-5
Tigers
83-67-741-35-542-32-258-48-624-18-1

Straight-Up (ML) History

overallhomeawayfavoriteunderdog
Guardians
85-7242-3443-3841-2343-46
Tigers
85-7246-3539-3764-4821-22

Last 5 Matchups

dateopponentscorespreadover/undermoneyline
Sep 23rdDETW 5-2+1.5 WO 6.5CLE +136
Sep 21st@MINL 2-6-1.5 LU 8.5MIN -143
Sep 20th@MINW 8-0-1.5 WU 8.5CLE -108
Sep 20th@MINW 6-0---
Sep 20th@MINW 6-2-1.5 WO 7.5CLE -113

Guardians vs. Tigers Injury Updates

Guardians Injuries

  • Ben Lively
    SP

    Lively is out with elbow

    Out

  • John Means
    SP

    Means is out with elbow

    Out

Tigers Injuries

  • Alex Cobb
    SP

    Cobb is out with hip

    Out

  • Reese Olson
    SP

    Olson is out with shoulder

    Out

  • Ty Madden
    SP

    Madden is out with shoulder

    Out

Tigers vs. Guardians Box Score
Tigers Player Stats
Projected
PITCHERPCIPKER
Jack Flaherty logoRJ.Flaherty, P834.163
Tyler Holton logoLT.Holton, P211.220
HITTERSH-ABRHRRBI
Parker Meadows logo1P.Meadows, CF0-2001
Gleyber Torres logo2G.Torres, 2B1-3000
Kerry Carpenter logo3K.Carpenter, DH0-3000
Spencer Torkelson logo4S.Torkelson, 1B1-3000
Riley Greene logo5R.Greene, LF1-2000
Wenceel Perez logo6W.Perez, RF0-2000
Zach McKinstry logo7Z.McKinstry, 3B0-2000
Dillon Dingler logo8D.Dingler, C1-2100
Trey Sweeney logo9T.Sweeney, SS1-2000
Guardians Player Stats
Projected
PITCHERPCIPKER
Tanner Bibee logoRT.Bibee, P105651
HITTERSH-ABRHRRBI
Steven Kwan logo1S.Kwan, LF1-3001
George Valera logo2G.Valera, DH1-3112
Jose Ramirez logo3J.Ramirez, 3B1-3000
Kyle Manzardo logo4K.Manzardo, 1B0-3000
Bo Naylor logo5B.Naylor, C0-3000
Gabriel Arias logo6G.Arias, SS0-3000
Daniel Schneemann logo7D.Schneemann, CF0-2000
CJ Kayfus logo8C.Kayfus, RF0-2000
Brayan Rocchio logo9B.Rocchio, 2B2-2200

Tigers vs. Guardians Odds Comparison

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Tigers at Guardians Team Totals

MatchupOverUnder
Tigers
85-72
N/A
N/A
Guardians
85-72
N/A
N/A