Diamondbacks vs Tigers Prediction, Odds: MLB Picks, Preview for Monday, July 28

Diamondbacks vs Tigers Prediction, Odds: MLB Picks, Preview for Monday, July 28 article feature image
Credit:

Photo by Charles LeClaire-Imagn Images. Pictured: Troy Melton

Starting soon
Odds Updating Soon
Matchup - 7/28 10:40pm UTCSpreadTotalMoneyline
+1.5-189
o9-101
+113
-1.5+155
u9-120
-135

The Arizona Diamondbacks (51-55) and Detroit Tigers (61-46) will face off in the MLB tonight. First pitch from Comerica Park is scheduled for 6:40 p.m. ET. The game will broadcast live on FDSDET.

Detroit is a -135 favorite to win outright on the moneyline, while Arizona is +115 to pull off the upset. The over/under is set at 9 total runs.

Continue below for my Diamondbacks vs Tigers predictions and MLB picks for Monday, July 28, as well as probable pitchers, betting trends, injury reports, and more.

Quickslip

Diamondbacks vs Tigers Picks, Prediction

  • Diamondbacks vs Tigers pick: First Five Innings Under 4.5 Runs (-110)

My Tigers vs. Diamondbacks best bet is on the game to stay under the first five innings total, with the best line currently available at DraftKings. But as always, make sure to find the best odds by checking our live MLB odds page.


Diamondbacks vs Tigers Odds for Monday, July 28

Diamondbacks Logo
Monday, July 28
6:40 p.m. ET
FDSDET
Tigers Logo
Diamondbacks Odds
SpreadTotalMoneyline
+1.5
-188
9
-102o / -120u
+115
Tigers Odds
SpreadTotalMoneyline
-1.5
+153
9
-102o / -120u
-135
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo

Diamondbacks vs Tigers Projected Starting Pitchers

LHP Eduardo Rodriguez (ARI)StatRHP Troy Melton (DET)
3-6W-L0-1
0.8fWAR (FanGraphs)-0.1
5.50/4.31ERA /xERA10.80/7.72
4.48/4.08FIP / xFIP6.69/3.28
1.65WHIP1.80
15.1K-BB%20.8
37.7GB%46.7
92Stuff+109
100Location+95

Arizona Diamondbacks vs Detroit Tigers MLB Preview

Arizona Diamondbacks Betting Preview

The Diamondbacks are stumbling into this series, having dropped four of their past five games.

However, a closer look shows the Diamonbacks' cold stretch has been much longer than a week.

What's deceiving about the Dbacks' numbers, especially against righties, is that they now lead the majors in wRC+, OPS, and ISO against them on the season, although they have dropped off significantly over the past month.

Over their last 30 games, Arizona ranks 25th in average, 14th in OPS and 15th in wRC+.

Their decline opens the door for a young right-hander in Troy Metlton to shine tonight.

Melton had a rough major league debut as the Pirates tagged him for six runs on seven hits over five innings. However, he flashed excellent stuff and struck out seven batters.

With debut jitters out of the way, we should see Melton have more success tonight, given he's catching this Diamondbacks lineup at the right time.


Detroit Tigers Betting Preview

As for the Tigers, it's a similar story. They come into this series with a 2-8 record over their last 10 ballgames, and despite a good matchup on paper, their recent stretch does not inspire much confidence.

For the season, Detroit has done damage against lefties, ranking fourth in wRC+ and OPS while sitting in seventh in ISO.

However, over the last month, southpaws have gotten the best of them.

In their last 30 games, the Tigers rank 28th in average and OPS, while placing 27th in wRC+.

This cold stretch has the potential to make any lefty look good, even Eduardo Rodriguez.

E-Rod has had a rough 2025 campaign. He comes into this outing with a 5.50 ERA and 1.65 WHIP.

However, he has done a good job of limiting hard contact, as his hard-hit rate is in the 88th percentile, which is impressive.

That amount of soft contact suggests he's due for better results, and his xERA of 4.31 and xFIP of 3.95 confirm he's pitched much better than his season ERA portrays.

There may be no better time for a lefty to face the Tigers than tonight. So, look for Rodriguez to get it right.


Diamondbacks vs Tigers Betting Predictions

As we've gone over, at first glance, this matchup appears to be a great one for both lineups.

However, the issue is that they are far from their best form right now and face two starters who can capitalize on that.

That disparity has given us a nice price on the under in the first five innings here as the starters are being overlooked.

Fade these ice-cold bats and take the under in the first five.

Diamondbacks vs Tigers Best Bet

  • F5 Under 4.5 (-110)

Diamondbacks vs Tigers Betting Trends



For the latest on MLB injuries, be sure to check out our MLB Injury Report page.

About the Author
Doug is a college football, college basketball and MLB contributor at the Action Network. He produces content centered around actionable advice with the goal of helping readers become better bettors. He studied journalism at Rutgers and has previously covered the New York Mets, Indianapolis Colts, and Mid-Atlantic region for Perfect Game.

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