The St. Louis Cardinals host the Arizona Diamondbacks on June 24, 2026. First pitch from Busch Stadium is scheduled for 7:45 p.m. ET. The game will be broadcast on CARD.
The Cardinals are favored by -118 on the moneyline and are +1.5 on the run line. The Diamondbacks are -102 on the moneyline and -1.5 on the run line. The total is set at 9 runs.
Find our MLB picks and Diamondbacks vs Cardinals prediction below, as well as probable pitchers, weather report, and more.
Diamondbacks vs Cardinals Prediction
- Diamondbacks vs Cardinals Pick: Matthew Liberatore Under 3.5 Strikeouts (-127)
Our Diamondbacks vs Cardinals best bet is on Matthew Liberatore to record three or fewer strikeouts tonight. Make sure to find the best odds by checking our live MLB odds page.
Diamondbacks vs Cardinals Odds
| Diamondbacks Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +158 | 9 -110o / -110u | -102 |
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -192 | 9 -110o / -110u | -118 |
- Diamondbacks vs Cardinals moneyline: Diamondbacks -102, Cardinals -118
- Diamondbacks vs Cardinals over/under: 9 (-110o / -110u)
- Diamondbacks vs Cardinals spread: Diamondbacks -1.5 (+158), Cardinals +1.5 (-192)
Diamondbacks vs Cardinals Probable Pitchers
| Mitch Bratt (LHP, ARI) | Stat | Matthew Liberatore (LHP, SL) |
|---|---|---|
| (MLB Debut) | W-L | 3-4 |
| fWAR (FanGraphs) | 0.1 | |
| ERA / xERA | 5.23 / 5.78 | |
| FIP / xFIP | 5.07 / 4.17 | |
| K-BB% | 12.5 | |
| GB% | 38.1 | |
| BABIP | .336 | |
| Stuff+ | 98 | |
| Location+ | 102 |
Diamondbacks vs Cardinals MLB Betting Preview
Action PRO projects Cardinals starter Matthew Liberatore for 2.85 strikeouts tonight against the Diamondbacks, giving us a 9.6% edge against the market when compared to his current prop line of over/under 3.5, which is good enough to mark the under with a B grade in our system.
He got pummeled by the Royals in his last outing, going only one and 2/3 innings, while allowing seven hits and seven runs (only five earned) with two strikeouts.
In June, Liberatore has a 10.50 ERA across three games.
Tonight, he will face an Arizona lineup that ranks 25th in wRC+ this season with a 91 rating, but is fourth in the majors in that same category against left-handed pitchers like Liberatore with a 108 rating.
So, expect the Diamondbacks to give him a hard time and, maybe, cut his start (and strikeouts) short.
Pick: Matthew Liberatore Under 3.5 Strikeouts (-127, DraftKings)
