The Minnesota Twins host the Houston Astros on May 18, 2026. First pitch from Target Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on SCHN.
The Astros are favored by -115 on the moneyline and by -1.5 on the run line. The Twins are -105 on the moneyline and +1.5 on the run line. The total is set at 9.5 runs.
Find my MLB picks and Astros vs Twins prediction below, as well as probable pitchers, weather report, and more.
Astros vs Twins Prediction
- Astros vs Twins Pick: Tatsuya Imai Under 4.5 Strikeouts (+104 , DraftKings)
My Astros vs Twins best bet is on Imai to record less than 5 strikeouts. Make sure to find the best odds by checking our live MLB odds page.
Astros vs Twins Odds
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -177 | 9.5 -103o / -117u | -105 |
| Twins Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +154 | 9.5 -103o / -117u | -115 |
- Astros vs Twins moneyline: Astros -105, Twins -115
- Astros vs Twins over/under: 9.5 (-103o / -117u)
- Astros vs Twins spread: Astros -1.5 (+154), Twins +1.5 (-177)
Astros vs Twins Probable Pitchers
| Tatsuya Imai | Stat | Kendry Rojas |
|---|---|---|
| 19-29 | W-L | 21-26 |
| -0.2 | fWAR (FanGraphs) | 0 |
| 9.24 / 6.62 | ERA / xERA | 2.45 / 5.48 |
| 6.65 / 5.49 | FIP / xFIP | 4.19 / 5.34 |
| 3.1 | K-BB% | 0 |
| 53.1 | GB% | 50 |
| .333 | BABIP | .444 |
| 88 | Stuff+ | 104 |
| 95 | Location+ | 74 |
Astros vs Twins MLB Betting Preview
Action PRO projects Astros starter Tatsuya Imai for 3.44 strikeouts in his matchup against the Twins tonight, giving us a strong 16.2% edge against the market when compared to his current prop line of over/under 4.5, which is good enough to tag the Under with an A grade in our system.
Astros vs Twins Pick, Betting Analysis
Imai has recorded 16 strikeouts through his first four appearances of the season, but his overall profile has not suggested a pitcher likely to generate high strikeout totals consistently at the MLB level.
The Astros right-hander has stayed under this number in three of his four outings so far, and this matchup presents another difficult spot to pile up punchouts against a Twins lineup capable of putting the ball in play consistently.
Pick: Tatsuya Imai Under 4.5 Strikeouts (+104 , DraftKings)
