A’s vs Tigers Prediction, Odds, Picks, MLB Betting Preview

A’s vs Tigers Prediction, Odds, Picks, MLB Betting Preview article feature image
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Credit: Imagn Images. Pictured: Athletics SP Luis Severino.

The Tigers host the A's on June 24, 2025. First pitch from Comerica Park is scheduled for 6:40 p.m. ET; the game will be broadcast on FDSDET and MLB.TV.

The Tigers enter as massive -330 favorites on the moneyline, while the A's are +257 to pull off the upset. The over/under, meanwhile, sits at 7.5.

Read our A's vs Tigers prediction and MLB pick below.

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A's vs Tigers Prediction, Picks

  • A's vs Tigers Picks: F5 Under 4 (-125, BetMGM)

My Tigers vs. A's best bet is on the first-five under. Make sure to find the best odds by checking our live MLB odds page.


A's vs Tigers Odds, Spread, Lines

Athletics Logo
Tuesday, June 24
6:40 p.m. ET
MLB.TV
Tigers Logo
Athletics Odds
Run LineTotalMoneyline
+1.5
+123
7.5
-108o / -112u
+257
Tigers Odds
Run LineTotalMoneyline
-1.5
-149
7.5
-108o / -112u
-330
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo

A's vs Tigers Pick, MLB Betting Preview

My handicap on this game has little to do with Tigers starting pitcher and AL Cy Young favorite Tarik Skubal. He’s the pitcher you don’t have to worry about in a matchup like this.

Instead, I’m targeting A’s starting pitcher, Luis Severino.

While I typically don’t put much stock into home/road splits for pitchers, I feel that Severino’s splits are essential this year, given how Sutter Health Park in Sacramento has affected Athletics’ pitchers.

Severino is not a great fit for his Triple-A ballpark, posting a 6.79 ERA across 10 home starts. However, he’s allowed just four total earned runs in six starts on the road this year. Opponents have posted a .827 OPS against Severino in Sacramento and a .480 OPS in any other park.

There’s likely some small-sample-size noise in those numbers, but ultimately, Severino is a much better pitcher on the road than at home.

Meanwhile, the Tigers’ bats have cooled off. They’ve lost five of their past eight games, struggling to hit the ball against Tampa over the weekend. So, Severino is catching them at the right time.

Meanwhile, Skubal should shut down the A’s lineup.

I love the F5 under 4 (-125) at BetMGM, but I’d bet the Under 3.5s available across the market as well.

Pick: F5 Under 4 (-125)


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About the Author
Collin Whitchurch is the manager of cross-platform content at Action Network, working directly with on-air talent, editors, and producers on efficient prioritization of coverage across the editorial, video, and audio mediums. Prior to his current role, Collin was the senior MLB editor at Action, managing the day-to-day content produced about baseball.

Follow Collin Whitchurch @cowhitchurch on Twitter/X.

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