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Red Sox vs Orioles Prediction, Pick, MLB Odds for Friday, September 4

Red Sox vs Orioles Prediction, Pick, MLB Odds for Friday, September 4 article feature image
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Gregory Fisher-Imagn Images. Pictured: Red Sox DH Roman Anthony

The Baltimore Orioles host the Boston Red Sox on September 4, 2026. First pitch from Oriole Park at Camden Yards is scheduled for 7:05 p.m. ET. The game will be broadcast on NESN.

The Red Sox are favored by -122 on the moneyline and by -1.5 on the run line. The Orioles are +104 on the moneyline and +1.5 on the run line. The total is set at 8.5 runs.

Find my MLB picks and Red Sox vs Orioles prediction below, as well as probable pitchers, weather report, and more.


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Red Sox vs Orioles Prediction

  • Red Sox vs Orioles Pick: Orioles ML (+104)

My Red Sox vs Orioles best bet is on Baltimore to win outright. Make sure to find the best odds by checking our live MLB odds page.


Red Sox vs Orioles Odds

Red Sox Logo
Friday, Sep 4
7:05 p.m. ET
NESN
Orioles Logo
Red Sox Odds
SpreadTotalMoneyline
-1.5
+138
8.5
-102o / -120u
-122
Orioles Odds
SpreadTotalMoneyline
+1.5
-166
8.5
-102o / -120u
+104
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Red Sox vs Orioles moneyline: Red Sox -122, Orioles +104
  • Red Sox vs Orioles over/under: 8.5 (-102o / -120u)
  • Red Sox vs Orioles spread: Red Sox -1.5 (+138), Orioles +1.5 (-166)

Red Sox vs Orioles Probable Pitchers

Ranger Suarez (LHP, BOS)StatShane Baz (RHP, BAL)
5-4W-L5-14
3.3fWAR (FanGraphs)3.4
3.64 / 3.75ERA / xERA4.01 / 4.05
3.10 / 3.66FIP / xFIP3.36 / 3.18
15.5K-BB%12.6
40.2GB%38.2
.308BABIP.317
94Stuff+98
106Location+103

Red Sox vs Orioles MLB Betting Preview

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Boston Red Sox Betting Preview

Ranger Suarez is struggling lately. He has a 5.72 ERA, backed by a 5.32 xERA, 5.14 FIP, and 5.36 xFIP since July 31. He is still having an excellent season overall, but this stretch is muddying what would have been another low-3.00 ERA year.

The Red Sox starter will face a Baltimore offense that is ninth against LHP (103 wRC+) this season and 11th in offense over the past 30 days (103 wRC+). Also, the Orioles just added lefty-masher Luis Robert Jr. to the lineup (career 137 wRC+ vs LHP).

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Baltimore Orioles Betting Preview

Shane Baz takes the mound for the Orioles, and he will look to drop his ERA below 4.00 tonight. Baz has rebounded from last season's 4.87 ERA and done well in his new home park.

Baz at home: 3.82 ERA, 13.2% K-BB, 3.11 FIP, 3.99 xFIP

His wOBA allowed at home is higher than on the road, but this is due to an unlucky .350 BABIP. Baz has allowed fewer HR at home (4) than on the road (7) and may build on a stretch of promising starts. Baz has a 3.60 ERA, backed by a 3.08 xERA, 3.50 FIP, and 3.51 xFIP since July 12.


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Red Sox vs Orioles Pick, Betting Analysis

Boston activated Roman Anthony and Trevor Story this week, yet just lost 2026 All-Stars Willson Contreras and Ceddanne Rafaela. They have the second-best offense in baseball this past month, but only the 11th-best in the past two weeks.

Much of Boston's recent production is a result of Mickey Gaspar's hot streak and, more recently, Adley Rutschman's two-homer day in his return to Baltimore on Thursday.

The Orioles didn't have several relievers available yesterday, but they should today, aside from Yennier Cano.

Pick: Orioles ML (+104, FanDuel)


Red Sox vs Orioles Weather


Get the latest coverage on MLB Weather.


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About the Author
Kevork MahserejianVerified Action Expert

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