Red Sox vs Phillies Odds, Picks, Predictions and Parlay

Red Sox vs Phillies Odds, Picks, Predictions and Parlay article feature image
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Photo by Bill Streicher-Imagn Images. Pictured: Bryce Harper

Starting soon
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Matchup - 7/21 10:45pm UTCSpreadTotalMoneyline
+1.5-106
o8-105
+187
-1.5-114
u8-115
-227

The Philadelphia Phillies host the Boston Red Sox on July 21, 2025. First pitch from Citizens Bank Park is scheduled for 6:45 p.m. ET; the game will be broadcast on NBCS-PH.

Zack Wheeler will start tonight for Philadelphia in the opener of this three-game series. Walker Buehler will oppose him for Boston.

Find my MLB betting preview and Red Sox vs Phillies prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Red Sox vs Phillies Picks and Predictions

  • Phillies ML
  • Bryce Harper 2+ Bases

Parlay Odds: +164


Red Sox vs Phillies Odds, Run Line, Over/Under

Red Sox Logo
Monday, July 21
6:45 p.m. ET
NBCS-PH
Phillies Logo
Red Sox Odds
SpreadTotalMoneyline
+1.5
-115
8.5
-106o / -115u
+176
Phillies Odds
SpreadTotalMoneyline
-1.5
-105
8.5
-106o / -115u
-218
Odds via DraftKings. Get up-to-the-minute MLB odds here.
DraftKings Logo

Red Sox vs Phillies Projected Starters

RHP Walker Buehler (BOS)StatRHP Zack Wheeler (PHI)
6-6W-L9-3
-0.6fWAR (FanGraphs)3.7
6.12 / 5.30ERA / xERA2.36 / 2.38
5.96 / 4.72FIP / xFIP2.69 / 2.62
1.56WHIP0.86
7.9K-BB%27.4
44.3GB%39.7
98Stuff+112
94Location+109

Red Sox vs Phillies Parlay Picks

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Moneyline: Phillies ML

The Phillies will hand the rock to their ace Wheeler on Monday.

He's in the Cy Young conversation once again this season. The veteran has posted an ERA of 2.36 and a WHIP of 0.86, which ranks second in the MLB.

Wheeler will deliver another strong start at home, where he's 6-1 with a 1.91 ERA this year.

Red Sox starter Buehler has struggled on the road this year, with an ERA of 8.66 in 35.1 innings.


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Bryce Harper 2+ Bases

The former MVP has been swinging a hot bat lately.

Bryce Harper has 12 hits over his last seven games, including eight extra-base hits.

The lefty veteran is 2-3 in his career against Buehler, with one home run and a double.


Red Sox vs Phillies Parlay

  • Phillies ML
  • Bryce Harper 2+ Bases

Parlay odds: +164 (DraftKings)


Red Sox vs Phillies Betting Trends


About the Author
Matt is a Senior Betting Analyst at Action Network. He has been in the betting industry for eight years and has worked as a Lead Betting Analyst for numerous companies over the years. Matt specializes in multiple sports, including NFL, NBA, MLB, NHL, NCAAF, NCAAB, UFC, Golf and NASCAR.

Follow Dead President Picks @DeadPresPicks on Twitter/X.

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