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Red Sox vs Blue Jays Prediction, Pick, Odds for Tuesday, September 23

Red Sox vs Blue Jays Prediction, Pick, Odds for Tuesday, September 23 article feature image
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Pictured: Lucas Giolito. (Credit: Arianna Grainey-Imagn Image)

The Toronto Blue Jays (90-66) host the Boston Red Sox (85-71) on September 23, 2025. First pitch from Rogers Centre is scheduled for 7:07 p.m. EDT; the game will be broadcast on NESN.

Find my MLB betting preview and Red Sox vs Blue Jays prediction below, as well as probable pitchers, betting trends, injury reports and more.

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Our Red Sox vs Blue Jays Prediction

  • Red Sox vs Blue Jays pick: Under 8

Our Red Sox vs Blue Jays best bet is on the under total runs. Make sure to find the best odds by checking our live MLB odds page.


Red Sox vs Blue Jays Odds

Red Sox Logo
Tuesday, Sep 23
7:07 p.m. ET
NESN
Blue Jays Logo
Red Sox Odds
SpreadTotalMoneyline
+1.5
-155
8
-105o / -115u
+140
Blue Jays Odds
SpreadTotalMoneyline
-1.5
+130
8
-105o / -115u
-165
Odds via bet365. Get up-to-the-minute MLB odds here.
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Red Sox vs Blue Jays Projected Starting Pitchers

RHP Lucas Giolito (BOS)StatRHP Kevin Gausman (TOR)
10-4W-L10-10
1.9fWAR (FanGraphs)3.7
3.46/5.00ERA /xERA3.38/3.69
4.17/4.50FIP / xFIP3.52/3.81
1.28WHIP1.01
11.2%K-BB%17.9%
37.8%GB%35.6%
92Stuff+100
99Location+103

Red Sox vs Blue Jays Prediction, Betting Analysis

The Toronto Blue Jays (-165) host the Boston Red Sox (+140) in Game 1 of a crucial three-game set on Tuesday night. The total is set at 8 runs, and with both teams in the thick of the playoff race, this matchup sets up well for a lower-scoring contest.

The Blue Jays already punched their ticket to October, clinching the American League’s first playoff berth with an 8-5 win over the Royals on Sunday. Toronto still has work to do, needing either one more win or a Boston loss to lock up the AL East. Meanwhile, the Red Sox enter with a magic number of five to clinch their own playoff spot.

The pitching matchup should keep runs in check. Lucas Giolito has been sharp against Toronto this season, posting a 2.08 ERA across two starts (13 innings, 3 ER allowed). Kevin Gausman counters for the Jays, and he was dominant in his last outing against Boston—8 scoreless innings with 10 strikeouts at Fenway Park back in April.

On top of the strong arms, this game also fits Evan Abrams’ “Wind Whisper Unders” system. Since 2020, the model has flagged unders in games where wind blows in at moderate speeds and cooler temperatures dampen offense, while the betting market shows steady downward pressure on the total without overwhelming public support.

That combination—weather suppressing power, sharp action leaning under, and the public not fully on board—has made this angle quietly profitable over multiple seasons.

MLB Icon
Evan Abrams / Bet Labs – Wind Whisper Unders
the over/under % is between 1% and 55%
the average wind speed is between 3 and 15 mph
the closing total is between 7 and 10
the game was played during the 2025 or 2024 or 2023 or 2022 or 2021 or 2020 season
the o/u change from open to close is between -2.5 and 0
the temperature is between 30 and 70 degrees
the wind direction is From Left or In or From Right
betting on the Under
the game is played during the Regular season
$12.344
WON
508-346-47
RECORD
59%
WIN%

Pick: Under 8 (-115, bet365)


Red Sox vs Blue Jays Betting Trends



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