The Houston Astros host the Chicago White Sox on June 10, 2025. First pitch from Daikin Park is scheduled for 8:10 p.m. ET; the game will be broadcast on SCHN.
Find my MLB betting preview and White Sox vs Astros prediction below, as well as probable pitchers, betting trends, injury reports and more.
My White Sox vs Astros Prediction
- White Sox vs Astros Picks: Under 8 (Bet at -112 | Play to 7.5 +100)
My White Sox vs Astros best bet is on the Under. Make sure to find the best odds by checking our live MLB odds page.
White Sox vs Astros Odds
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -155 | 7.5 -120o / +100u | +145 |
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +125 | 7.5 -120o / +100u | -180 |
White Sox vs Astros Projected Starting Pitchers
| Shane Smith (CHW) | Stat | Lance McCullers Jr. (HOU) |
|---|---|---|
| 2-3 | W-L | 1-1 |
| 1.3 | fWAR (FanGraphs) | 0.3 |
| 2.45 / 3.59 | ERA / xERA | 4.44 / 4.41 |
| 3.52 / 4.05 | FIP / xFIP | 3.93 / 3.63 |
| 1.14 | WHIP | 1.40 |
| 13.4 | K-BB% | 18.4 |
| 43.2 | GB% | 43.8 |
| 96 | Stuff+ | 102 |
| 101 | Location+ | 94 |
White Sox vs Astros Prediction, Betting Analysis
I project this total right around 7.25, so I’m looking to bet Under 7.5 at any plus-money price.
Astros starting pitcher Lance McCullers Jr. has been so much better in his past few starts than he was in his first few starts. Remember, he hadn’t pitched since 2022, so he needed some time to settle in.
However, the advanced pitching model metrics have come around.
| Lance McCullers Jr. | Stuff+ / Location+ | Pitching+ | botERA |
|---|---|---|---|
| First Three Starts | 95 / 83 | 83 | 5.45 |
| Last Three Starts | 108 / 102 | 106 | 3.18 |
He’s struck out 19 and walked only two across his past two starts behind a nasty slider (125 Stuff+) and knuckle-curve (123 Stuff+) — he can spin the ball like crazy and get guys to swing over the top and miss.
Meanwhile, the Astros' lineup is in their much lesser split against a righty. They’ve posted a 123 wRC+ against southpaws this year but a 97 against righties.
That means it’s a good matchup for White Sox starting pitcher Shane Smith, who has been an effective league-average pitcher behind his plus-changeup — he’s pitched to around a 3.60 xERA.
Pick: Under 8 (Bet at -112 | Play to 7.5 +100)
Moneyline
No play.
Run Line (Spread)
No play.
Over/Under
I like the Under in this matchup.
