The Tampa Bay Rays host the Chicago White Sox on July 21, 2025. First pitch from George M. Steinbrenner Field is scheduled for 7:35 p.m. EDT; the game will be broadcast on FDSSUN.
Read our White Sox vs Rays prediction and MLB player prop pick below.
My White Sox vs Rays Prediction
- White Sox vs Rays Picks: Sean Burke Over 3.5 Strikeouts (-150, Caesars)
My White Sox vs Rays best bet is on Sean Burke's strikeout prop. Make sure to find the best odds by checking our live MLB odds page.
White Sox vs Rays Odds
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -115 | 9 -100o / -120u | +180 |
| Rays Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -105 | 9 -100o / -120u | -220 |
Chris Prince’s White Sox vs Rays Preview
The bar is low for Sean Burke at 3.5 strikeouts, so I don't mind paying the juice.
Burke has struck out at least four hitters in nine of his past 10 starts and 13 of 19 on the year.
Burke’s strikeout rate is much higher against left-handed hitters, and Tampa should have six southpaws in the lineup on Monday.
The Rays have been a middling matchup for strikeouts against right-handed pitchers, but there are four bats with a strikeout rate over 23% against the side, three of whom are lefties.
Pick: Sean Burke Over 3.5 Strikeouts (-150, Caesars)
