The Minnesota Twins host the Detroit Tigers on April 6, 2026. First pitch from Target Field is scheduled for 7:40 p.m. EDT. The game will be broadcast on DSN.
The Twins are favored by -120 on the moneyline and by -1.5 on the run line. The Tigers are +102 on the moneyline and +1.5 on the run line. The total is set at 7 runs.
Find my MLB picks and Tigers vs Twins prediction below, as well as probable pitchers, weather report, and more.
Tigers vs Twins Prediction
- Tigers vs Twins Pick: Twins Moneyline (-120)
My Tigers vs Twins best bet is on Minnesota to win outright. Make sure to find the best odds by checking our live MLB odds page.
Tigers vs Twins Odds
| Tigers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -207 | 7 -115o / -105u | +102 |
| Twins Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +169 | 7 -115o / -105u | -120 |
- Tigers vs Twins spread: Twins -1.5 (+169), Tigers +1.5 (-207)
- Tigers vs Twins over/under: 7 (-115o / -105u)
- Tigers vs Twins moneyline: Tigers +102, Twins -120
Tigers vs Twins Projected Starting Pitchers
| RHP Casey Mize (DET) | Stat | RHP Joe Ryan (MIN) |
|---|---|---|
| 0-0 | W-L | 0-1 |
| 0.1 | fWAR (FanGraphs) | 0.4 |
| 1.50/5.01 | ERA /xERA | 4.82/3.74 |
| 3.36/1.89 | FIP / xFIP | 2.02/4.25 |
| 1.00 | WHIP | 1.29 |
| 31.8% | K-BB% | 20.5% |
| 54.5% | GB% | 20.0% |
| 92 | Stuff+ | 107 |
| 96 | Location+ | 106 |
Tigers vs Twins Preview
The Twins money line offers a modest edge here. I project the line closer to -135, but since you can currently find it at -120, I would take that up to -125.
Unfortunately, there isn’t any value on the first-five line; otherwise, I would be happy to simply back Joe Ryan against Casey Mize for the first five innings. However, that sits at -135, which aligns exactly with my projections.
Ryan certainly holds the advantage over Mize, with a 3.75 projection compared to Mize’s 4.1, putting Ryan a full tier ahead.
Regarding the offenses, while Minnesota still has the roster they started the season with, the two lineups are not drastically different.
The most unusual discrepancy between these teams is that the Tigers project as one of my worst base-running teams. It is a bit counterintuitive when you look at their lineup—Parker Meadows runs really well and Riley Greene runs decently—but the metrics aren't there.
Tigers vs Twins Picks
The play feels like a bit of a contradiction, primarily because I lack confidence in betting against a Tigers team projected to win the division while simultaneously backing a Twins team whose season win total I have the under on.
That said, for today specifically, I make the Twins closer to -135. Therefore, anything -125 or better on the Minnesota money line is a viable wager.
It isn't one of my favorite plays on the board, but there is certainly a mathematical edge.
Pick: Twins Moneyline (-120)
