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Home Run Picks Today: 5 MLB Bets for Royals-Tigers, Rangers-Athletics, More for April 15

Home Run Picks Today: 5 MLB Bets for Royals-Tigers, Rangers-Athletics, More for April 15 article feature image
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Apr 5, 2026; West Sacramento, California, USA; Athletics catcher Shea Langeliers (23) celebrates on the way to home plate against the Houston Astros during the tenth inning at Sutter Health Park. Mandatory Credit: Neville E. Guard-Imagn Images

It's Wednesday, so you know I've got some bangers.

Read on for my Home Run Picks Today for Wednesday, April 15.

Home Run Picks Today

In the table below, you'll find each of our MLB staff's top player prop picks from today's slate of games. Click on any pick or team logo to navigate to a specific bet discussed in this article.

Time (ET)Player Prop
6:40 PM
6:40 PM
7:05 PM
7:40 PM
9:40 PM
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game.
Playbook


Nationals vs. Pirates Home Run Picks Today

Washington Nationals Logo
Wednesday, April 15
6:40 PM ET
MLB.TV
Pittsburgh Pirates Logo
Header First Logo

Oneil Cruz

Home Run

This spot for the lefties on the Pirates is one of the best on the board.

Jake Irvin has been one of the best matchups for lefty power in the league for years, allowing a massive 1.97 HR/9 in his career.

The weather in Pittsburgh should be great for hitting, with temps in the low-80s, wind blowing out to left, and good humidity.

Oneil Cruz has been great to start the season, and I make the fair odds on this home run prop under +300.

Pick: Oneil Cruz Home Run


Royals vs. Tigers HR Picks Today

Kansas City Royals Logo
Wednesday, April 15
6:40 PM ET
MLB.TV
Detroit Tigers Logo
Header First Logo

Kevin McGonigle

Home Run

The lefties for the Tigers also get one of the best matchups on the board.

Seth Lugo was probably the worst pitcher in the league last season at suppressing power to lefties, giving up a massive 2.31 HR/9. While he is due for some positive regression, he grades out as an above-average matchup for lefty power, and the weather in Detroit should be about average for hitting.

I make the fair odds on this home run prop under +500.

Pick: Kevin McGonigle Home Run


Angels vs. Yankees Player Prop Pick

Los Angeles Angels Logo
Wednesday, April 15
7:05 PM ET
MLB.TV
New York Yankees Logo
Header First Logo

Mike Trout

Home Run

Mike Trout has been incredible to start the season, and the underlying numbers have been the best of his career.

This is an ideal spot, with a great matchup and great weather.

The temps will be in the low-80s, and the wind should be blowing out at nine MPH, so the ball should be flying in New York tonight.

Luis Gil hasn't allowed a ton of bombs in his career, but he's due for some negative regression and grades out as an above-average matchup for righty power.

I make the fair odds on this home run prop under +500.

Pick: Mike Trout Home Run


Rays vs. White Sox MLB Home Run Pick

Tampa Bay Rays Logo
Wednesday, April 15
7:40 PM ET
MLB.TV
Chicago White Sox Logo
Header First Logo

Munetaka Murakami

Home Run

The weather in Chicago is a concern, but if this game plays, then these odds on the White Sox power lefties are a bit too high.

The Rays are using an opener, but Jesse Scholtens is coming in behind him and grades out as a plus matchup for lefty power.

Munetaka Murakami has been one of the best power hitters in the league, and I make the fair odds on this home run prop around +350.

Pick: Munetaka Murakami Home Run


Rangers vs. Athletics MLB Player Prop

Texas Rangers Logo
Wednesday, April 15
9:40 PM ET
MLB.TV
Oakland Athletics Logo
Header First Logo

Shea Langeliers

Home Run

Shea Langeliers has slowed down after his hot start, but the power is absolutely there, and he may end up with more than 40 bombs this season.

The matchup today against Kumar Rocker is a plus, as he gave up 1.45 HR/9 last season.

The ballpark is great for power, and the weather is a slight plus with the wind blowing out to left field.

I make the fair odds on this home run prop around +350.

Pick: Shea Langeliers Home Run


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About the Author
Grant NeifferVerified Action Expert

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