The Seattle Mariners host the Houston Astros on April 11, 2026. First pitch from T-Mobile Park is scheduled for 9:40 p.m. EDT. The game will be broadcast on SEAM.
Find my MLB picks and Astros vs Mariners prediction below, as well as probable pitchers, weather report, and more.
Astros vs Mariners Prediction
- Astros vs Mariners Pick: Luis Castillo Over 5.5 Strikeouts
Astros vs Mariners Odds
| Astros Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -166 | 7.5 -115o / -105u | +124 |
| Mariners Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +138 | 7.5 -115o / -105u | -146 |
Astros vs Mariners Polymarket Odds
Current odds: HOU 42% · SEA 59% · MLB
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Astros vs Mariners MLB Betting Preview
By Derek Carty
THE BAT X is forecasting 6.20 strikeouts for Castillo.
Oddsmakers are implying 5.44 strikeouts, so I believe there is value.
If you take the over, you’d be projected to win 59% of the time, resulting in a 28% ROI with an expected value of $28.28 (based on a $100 wager).
This play is good down to at least -107.
Love THE BAT X? Get all of Carty’s sports betting projections at EV Analytics!
Pick: Luis Castillo Over 5.5 Strikeouts
