The St. Louis Cardinals host the Kansas City Royals on on June 3, 2025. First pitch from Busch Stadium is scheduled for 7:45 p.m. ET; the game will be broadcast on FDSKC.
Find my MLB betting preview and Royals vs Cardinals prediction below, as well as probable pitchers, betting trends, injury reports and more.
My Royals vs Cardinals Prediction
- Royals vs Cardinals picks: Royals ML +125 (BetRivers)
My Royals vs Cardinals best bet is the Royals moneyline. Make sure to find the best odds by checking our live MLB odds page.
Royals vs Cardinals Odds
| Royals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -185 | 8.5 -115o / -105u | +118 |
| Cardinals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +150 | 8.5 -115o / -105u | -145 |
Royals vs Cardinals Projected Starting Pitchers
| Michael Lorenzen (KC) | Stat | Andre Pallante (STL) |
|---|---|---|
| 3-6 | W-L | 4-3 |
| 0.5 | fWAR (FanGraphs) | 0.1 |
| 4.33 / 4.19 | ERA /xERA | 4.23 / 4.51 |
| 4.51 / 4.33 | FIP / xFIP | 4.73 / 3.72 |
| 1.40 | WHIP | 1.36 |
| 12.1 | K-BB% | 7.2 |
| 39.7 | GB% | 63.6 |
| 94 | Stuff+ | 92 |
| 103 | Location+ | 102 |
Royals vs Cardinals Prediction, Betting Analysis
According to Evan Abrams' "Road 'Dogs Interleague" system, the Royals are the play on the moneyline for this Tuesday MLB clash.
This system lights up in interleague instances, but with the Royals coming off of a loss to the Tigers and this being the first game of their three-game set against the Cards, it's the perfect spot to back the 'dog.
This system is +$5,993 since it's inception, with an ROI of 2.5%, giving it a solid history of picking road underdogs.
With Michael Lorenzen on the hill against Andre Pallante, expect the Royals to come out on top on the moneyline.
Pick: Royals ML +120
Moneyline
Expect the Royals to win this interleague matchup straight up.
Run Line (Spread)
There's no pick for the run line.
Over/Under
There's no pick for the total.
