Royals vs Cardinals Game 1 Prediction, Pick, Odds for Thursday, June 5

Action Network Staff

Updated:

Jun 05, 2025, 01:03 PM EDT

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Royals vs Cardinals Game 1 Prediction, Pick, Odds for Thursday, June 5 article feature image

MLB

Credit:

Brad Rempel-Imagn Images. Pictured: Noah Cameron.

The St. Louis Cardinals host the Kansas City Royals on Thursday, June 5, 2025. First pitch for Game 1 of the doubleheader from Busch Stadium is scheduled for 1:45 p.m. ET; the game will be broadcast on FanDuel Sports Kansas City/Midwest.

Find my Royals vs Cardinals prediction for Game 1 on Thursday below.

Editor's Note: This game was originally scheduled to be played on Wednesday but was postponed due to inclement weather. Noah Cameron and Miles Mikolas remain the probable starting pitchers for the Royals and Cardinals, respectively.

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My Royals vs Cardinals Prediction

Royals vs Cardinals Picks: Royals Moneyline +108

My Royals vs Cardinals best bet is on Royals moneyline. Make sure to find the best odds by checking our live MLB odds page.

Royals vs Cardinals Odds

Thursday, Jun 5

1:45 p.m. ET

FDSKC

Royals Odds
Spread	Total	Moneyline
+1.5 -192	8.5 -102o / -118u	+110

Cardinals Odds
Spread	Total	Moneyline
-1.5 +160	8.5 -102o / -118u	-130

Odds via DraftKings. Get up-to-the-minute MLB odds here.

Royals vs Cardinals Projected Starting Pitchers

Noah Cameron (KC)	Stat	Miles Mikolas (STL)
2-1	W-L	4-2
0.4	fWAR (FanGraphs)	1.0
1.05 / 3.14	ERA /xERA	3.90 / 4.33
3.77 / 4.50	FIP / xFIP	3.52 / 4.90
0.82	WHIP	1.25
8.2	K-BB%	7.7
38.9	GB%	36.7
93	Stuff+	88
102	Location+	107

Cardinals vs Royals Game 1 Prediction, Preview

Evan Abrams' system called "Road Dogs Interleague" is lighting up for this Royals vs. Cardinals matchup on Wednesday at Busch Stadium.

The second game of this three-game set comes after the Royals scored 10 runs on the Cardinals on Tuesday evening, winning 10-7.

This system is projecting yet another victory for Kansas City on Wednesday.

The good news is this system is +$6259 with a 2.6% ROI since its inception, making this a solid target for your MLB betting card.

the game was played during the 2025 or 2024 or 2023 or 2022 or 2021 or 2020 or 2019 or 2018 or 2017 or 2016 season

the team is the Dog

the team is the Visitor team

the game is a Non-Conference game

the game is played during the Regular season

$6,259

WON

1040-1374-0

RECORD

43%

WIN%

View System

Royals vs Cardinals Game 1 Pick, Best Bet: Royals ML +108

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Moneyline

I'm taking the underdog on the moneyline.

Run Line (Spread)

I don't have a play on the run line.

Over/Under

I don't have a play on the total.

Royals vs Cardinals Betting Trends

Royals vs Cardinals Weather

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Action Network Staff

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