The San Diego Padres (87-71) host the Milwaukee Brewers (95-63) on September 24, 2025. First pitch from PETCO Park is scheduled for 4:10 p.m. EDT; the game will be broadcast on FDSWI.
Find my MLB betting preview and Brewers vs Padres prediction below, as well as probable pitchers, betting trends, injury reports and more.
Our Brewers vs Padres Prediction
- Brewers vs Padres pick: Under 8
Our Brewers vs Padres best bet is on the under total runs. Make sure to find the best odds by checking our live MLB odds page.
Brewers vs Padres Odds
| Brewers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -200 | 8 -105o / -115u | +105 |
| Padres Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +165 | 8 -105o / -115u | -125 |
Brewers vs Padres Projected Starting Pitchers
| RHP Chad Patrick (MIL) | Stat | RHP Dylan Cease (SDP) |
|---|---|---|
| 3-8 | W-L | 8-12 |
| 2.4 | fWAR (FanGraphs) | 3.1 |
| 3.66/3.91 | ERA /xERA | 4.64/3.48 |
| 3.61/4.05 | FIP / xFIP | 3.64/3.59 |
| 1.28 | WHIP | 1.32 |
| 16.8% | K-BB% | 19.7% |
| 31.3% | GB% | 36.2% |
| 105 | Stuff+ | 108 |
| 99 | Location+ | 100 |
Brewers vs Padres Prediction, Betting Analysis
This is Game 3 of the set, with the Padres taking the first two matchups — 5-4 in the opener and 7-0 in Game 2. In Tuesday’s win, Ryan O’Hearn launched a grand slam as one of three San Diego homers, while Randy Vásquez and two relievers combined on a four-hitter to blank Milwaukee.
The Padres have now won four straight overall, while the Brewers’ loss ensured there will be no 100-game winners across MLB this season.
Chad Patrick will get the start for Milwaukee, while Dylan Cease takes the mound for San Diego. Cease enters his final regular-season outing leading all qualified starters with 11.4 strikeouts per nine innings.
The angle here lies on the total. This matchup fits the Contrarian Unders for Winning Teams, Later in Series system from Evan Abrams. The strategy highlights unders in Game 2 or later of MLB series when both teams have winning records.
The logic is straightforward: quality pitching staffs, tighter game scripts, and public bias toward the over — especially with two playoff-bound clubs — create contrarian value on the under.
Pick: Under 8 (-115, bet365)
Brewers vs Padres Betting Trends
