The Chicago White Sox host the Minnesota Twins on September 4, 2026. First pitch from Rate Field is scheduled for 7:40 p.m. ET. The game will be broadcast on CHSN.
The White Sox are favored by -120 on the moneyline and by -1.5 on the run line. The Twins are +100 on the moneyline and +1.5 on the run line. The total is set at 9 runs.
Find my MLB picks and Twins vs White Sox prediction below, as well as probable pitchers, weather report, and more.
Twins vs White Sox Prediction
- Twins vs White Sox Pick: Munetaka Murakami 1+ Home Runs (+270)
My Twins vs White Sox best bet is on Munetaka Murakami to hit a homer. Make sure to find the best odds by checking our live MLB odds page.
Twins vs White Sox Odds
| Twins Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -200 | 9 -110o / -110u | +100 |
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +165 | 9 -110o / -110u | -120 |
- Twins vs White Sox moneyline: Twins +100, White Sox -120
- Twins vs White Sox over/under: 9 (-110o / -110u)
- Twins vs White Sox spread: Twins +1.5 (-200), White Sox -1.5 (+165)
Twins vs White Sox Probable Pitchers
| Zebby Matthews (RHP, MIN) | Stat | Erick Fedde (RHP, CHW) |
|---|---|---|
| 9-8 | W-L | 7-8 |
| 0.7 | fWAR (FanGraphs) | -0.3 |
| 4.58 / 4.52 | ERA / xERA | 4.16 / 4.68 |
| 4.60 / 4.03 | FIP / xFIP | 5.16 / 4.72 |
| 13.1 | K-BB% | 8.1 |
| 44.0 | GB% | 39.3 |
| .282 | BABIP | .273 |
| 95 | Stuff+ | 89 |
| 101 | Location+ | 108 |
Twins vs White Sox MLB Betting Preview, Prediction
This is a great spot for Munetaka Murakami, and these odds are far too high.
Twins starter Zebby Matthews is a well-above-average matchup for lefty power, as he has allowed 1.51 HR/9 this season and a massive 2.05 HR/9 in his career.
The weather should be great for hitting in Chicago, with wind blowing out at 6 mph and temperatures in the high-80s.
I have the true odds for the White Sox 1B at around +240, making this a great bet.
Pick: Munetaka Murakami 1+ Home Runs (+270, bet365)
