We have an all-day, 15-game MLB slate on Wednesday, with plenty of home run picks.
I'm bringing you bangers for up to six matchups, including Yankees vs. Twins (1:40 p.m ET), Athletics vs. Rays (6:40 p.m ET), and Mariners vs. Angels (9:38 p.m. ET).
Read on for my 6 MLB Home Run Picks Today.
MLB Home Run Picks Today
In the table below, you'll find each of Grant Neiffer's top home run prop picks from today's slate of games. Click on any pick or team logo to navigate to a specific bet discussed in this article, and download the Action Network app for more picks and analysis.
| Game | Time (ET) | Pick |
|---|---|---|
  | 1:40 PM | |
  | 3:07 PM | |
  | 6:40 PM | |
  | 6:40 PM | |
  | 7:10 PM | |
  | 9:38 PM | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Yankees vs Twins Prediction, Pick
While the weather is a downgrade in this game, that's not nearly enough to get me off Aaron Judge in this spot.
Twins starter Zebby Matthews has been a gas can for power this season, allowing a high 1.66 HR/9 to righties.
Judge finally got one last night after struggling in his first five games back, but he's the best home run hitter in the league. I have the true odds for the Yankees RF at under +300.
Pick: Aaron Judge Home Run
| | | | | |
Tigers vs Blue Jays Prediction, Pick
This is a great spot for Kevin McGonigle, and these odds are way too high.
Max Scherzer has been better recently, but he's still been a gas can for lefty power this season (1.99 HR/9). While the Blue Jays SP has only allowed a few dingers since the All-Star Break, he's gotten very lucky and is due for heavy negative regression.
I have the true odds for the Tigers 3B at around +450.
Pick: Kevin McGonigle Home Run
| | | | | |
Athletics vs Rays Prediction, Pick
We don't have a huge sample size of Athletics starter Brady Basso in the majors, but he's been an average matchup for righty power and grades out around a 1.50 HR/9 pitcher to righties.
I don't love this ballpark, but Junior Caminero is one of the best HR hitters in the league, and I have the true odds for the Rays 3B at under +300.
Pick: Junior Caminero Home Run
| | | | | |
Brewers vs Pirates Prediction, Pick
This is a tough spot overall, but it's a good spot for lefty power, so Brandon Lowe can take advantage.
Brewers SP Logan Henderson is great, but he's an extreme fly-ball pitcher and has allowed an above-average 1.26 HR/9 to lefties this season.
This ballpark isn't great for power, but the weather should be above average for hitting, with temperatures in the low-80s and heavy humidity.
I have the true odds for the Pirates 2B at around +420.
Pick: Brandon Lowe Home Run
| | | | | |
Orioles vs Mets Prediction, Pick
This is a great spot, and these odds are far too high.
Orioles starter Chris Bassitt has been a gas can for lefty power for years, allowing more than a 1.50 HR/9 since 2023.
The weather in New York should be a plus for hitting, with wind blowing out at 8 mph, and Juan Soto is one of the best home run hitters in the league.
I have the true odds for the Mets LF at around +270.
Pick: Juan Soto Home Run
| | | | | |
Mariners vs Angels Prediction, Pick
This is a great spot, and these odds are a bit too high.
Angels SP Yusei Kikuchi hasn't been horrible at suppressing righty power this season, but historically, he's been a matchup that is well above average for righty power.
Randy Arozarena has been one of the best HR hitters in the league since the All-Star Break, and I have the true odds for the Mariners LF at around +400.
Pick: Randy Arozarena Home Run
| | | | | |
