We love Wednesdays on the diamond.
There are games to bet on all day, from Padres-Pirates at Noon to Tigers-Twins after Sundown.
Check out our four best bets for today's games below.
MLB Picks, Predictions
The team logos in the table below represent the matchups our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.
| Game | Time (ET) | Pick |
|---|---|---|
  | 2:35 PM | |
  | 12:35 PM | |
  | 1:35 PM | |
  | 7:05 PM | |
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game. | ||
Mariners vs. Rangers Moneyline Picks
By Sean Zerillo
We cashed an easy under at Progressive Field on Tuesday afternoon, with temperatures around 32 degrees at first pitch, and 11 MPH winds blowing in from center field.
Temperatures are a bit warmer (46 degrees at first pitch), and the wind has flipped toward left field (7-8 mph) for Wednesday, but I still show a substantial edge on the Under. I would have projected the total around 7.2 in weather-neutral conditions, but I set it closer to 6.33 after factoring in the cooler temperatures and low humidity — take Under 7 to -115.
Both offenses project worse against left-handed pitching as opposed to righties. Still, Cleveland takes the bigger hit against southpaw pitching (a 10-point reduction in wrC+) compared to Kansas City (projected two points better against righties).
Cole Ragans (projected FIP range from 3.23 to 3.60; projected K-BB% of 18.9% to 22.7%) projects as the better arm than Joey Cantillo (projected ranges from 3.72 to 4.11 and 13.9% to 15.4%), and I also give the Royals a slight bullpen edge with fatigued relievers on either side of the matchup.
Take the Royals in the first five innings (F5) to -140 and/or play their full game line to -120.
Read Sean Zerillo's full Opening Pitch column for Wednesday here:
Pick: Mariners ML (-133 or Better) | Under 7 (-115 or Better)
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Padres vs. Pirates Moneyline Prediction
By Sean Paul
I'm rolling with the Pirates.
They match up well against Michael King, as Brandon Lowe, Oneil Cruz, and Ryan O'Hearn should be able to handle the right-handed pitcher.
The line shows two evenly matched teams, but the Pirates look like the better squad.
Read Sean's full Padres-Pirates breakdown here:
Pick: Pirates ML (-130 or Better)
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Brewers vs. Red Sox Over/Under Picks
This game triggered one of our Action PRO betting systems, powered by Evan Abrams.
In the early months of the MLB season (March and April), cold weather (between 1 and 50 degrees) creates ideal conditions for unders.
Pitchers tend to be ahead of hitters at the start of the season, and colder air can suppress offensive production by reducing ball carry.
This system further isolates day games (12 PM to 4 PM) when shadows and cool starts give pitchers an additional edge — especially as hitters may take longer to get loose.
Taken together, these filters identify a recurring edge that has yielded a positive long-term ROI when consistently betting the under.
It is bone-chilling cold up in the Northeast during this time of year, and Fenway is no different. We’re expecting temperatures in the mid-40s for Wednesday’s game with winds blowing in from right field — not ideal for hitting.
Based on the weather report, BallParkPal projects a -51% home run factor, which should keep scoring down.
Also, I think Sonny Gray looked excellent in his last start against San Diego, tossing six shutout innings while allowing only two hits. He’s a guy who has had struggles with the long ball over the past two seasons (1.19 HR/9 allowed, 14.4% HR/FB rate allowed), so Wednesday’s weather should help him tremendously.
Want more PRO betting systems? Sign up for an Action PRO subscription today:
Pick: Under 7.5 (-115 or Better)
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Athletics vs. Yankees Total Picks
Our own Sean Zerillo projects a decent edge on the Over in this matchup.
While the consensus line sits around 8.5 with low juice toward the Over, Zerillo projects nearly 9.1 runs for the game, representing a nearly 3% edge against the market.
As a reminder, you can see all of Zerillo's MLB game projections with an Action PRO Subscription. Find his projected lines every day on the PRO Projections tab.
Pick: Over 8.5 (-112 or Better)
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