HomeRight ArrowMLB

MLB Picks, Predictions Today: Best Bets for Mariners vs Cardinals, Tigers vs Reds, More for Saturday, April 25

MLB Picks, Predictions Today: Best Bets for Mariners vs Cardinals, Tigers vs Reds, More for Saturday, April 25 article feature image
9 min read
Credit:

Jerome Miron, Nathan Ray Seebeck, Lon Horwedel and Jonathan Hui-Imagn Images. Pictured: Mariners CF Julio Rodriguez (top left), Tropicana Field in Tampa Bay (top right), Tigers SS Kevin McGonigle (bottom left), Dodgers SP Roki Sasaki (bottom right)

We are back with a 14-game slate on Saturday, starting with Red Sox vs. Orioles at 12:05 p.m. ET and closing with three games at 7:15 p.m. ET.

Our experts have analyzed the matchups and found great options for Saturday.

Below are five expert MLB picks and predictions for today's slate of games.


MLB Picks, Predictions Today

The team logos in the table below represent each of the matchups that our MLB betting staff is targeting from today's slate of games. Click on the team logos for any of the matchups below to navigate to a specific bet discussed in this article.

GameTime (ET)Pick
Seattle Mariners LogoSt. Louis Cardinals Logo
2:15 PM
Cleveland Guardians LogoToronto Blue Jays Logo
3:07 PM
Minnesota Twins LogoTampa Bay Rays Logo
4:10 PM
Detroit Tigers LogoCincinnati Reds Logo
7:15 PM
Chicago Cubs LogoLos Angeles Dodgers Logo
7:15 PM
Action Logo
All Day
Specific betting recommendations come from the sportsbook offering preferred odds as of writing. Always shop for the best price using our MLB Odds page, which automatically surfaces the best lines for every game.
Playbook


Mariners vs Cardinals ML Prediction

Seattle Mariners Logo
Saturday, April 25
2:15 PM ET
MLB.TV
St. Louis Cardinals Logo
Mariners ML (-149 or Better)
DraftKings Logo

By Sean Paul

Bryan Woo draws the start for the Mariners. He's an absolute stud Cy Young candidate, boasting a 2.25 ERA with a 2.48 xERA and a 2.27 FIP. He also limits the opponent to a .204 batting average and walks hitters 4% of the time.

The Mariners' offense is still pretty strong, ranking 13th in MLB with a 102 wRC+. The good thing? It should only improve from here, as Julio Rodriguez and Cal Raleigh are too good of hitters to have posted a wRC+ below 100.

The fans in St. Louis must be excited with their team posting a 14-11 record to start the season. This was supposed to be a rebuilding season for the Cardinals, but the emergence of Jordan Walker and JJ Wetherholt has made them competitive.

The breakout leap for Matthew Liberatore has yet to happen. The tall southpaw has a 3.67 ERA, a 4.69 ERA, and a 5.48 xERA. He just needs so much to go his way to have a good outing due to his 5.33 K/9. Pinpoint command held Liberatore above water last year, but his walk rate increased from 6% to 13%.

I just think the Cardinals are performing above their level right now. Walker will get hot again, but can he replicate his performance from earlier? Probably not. Plus, the pitching is a problem. Liberatore likely only goes five or six innings at most, which will expose a shaky Cardinals bullpen.

The advantage lies with the Mariners in the starting pitching department with Woo over Liberatore. I also have more faith in the Mariners' lineup to hit Liberatore, who will face regression soon enough. With the line sitting at Seattle -148, it's still plenty good enough to take them with its ace on the hill.

Read Paul's full Mariners-Cardinals breakdown here:

Mariners vs Cardinals Prediction, Pick, MLB Odds for Saturday, April 25 Image

Pick: Mariners ML (-149 or Better)



Guardians vs Blue Jays Best Bet

Cleveland Guardians Logo
Saturday, April 25
4:10 PM ET
MLB.TV
Toronto Blue Jays Logo
Miles Straw Under 0.5 Hits (+114 or Better)
DraftKings Logo

By Derek Carty

There may be some value in Miles Straw's hits prop.

THE BAT X is projecting the Blue Jays right fielder to record 0.56 hits, and oddsmakers are implying 0.77.

The model believes there is a 57% chance he records fewer than one hit.

There is great value here. This play is good down to at least -107.

Love THE BAT X? Get all of Carty's sports betting projections at EV Analytics!

Pick: Miles Straw Under 0.5 Hits (+114 or Better)



Twins vs Rays Top Projected Player Edge

Minnesota Twins Logo
Saturday, April 25
4:10 PM ET
MLB.TV
Tampa Bay Rays Logo
Bailey Ober Under 4.5 Strikeouts (-154 or Better)
FanDuel Logo

By Action PRO

PRO projects Bailey Ober for 3.4 strikeouts in the Twins matchup against the Rays this afternoon, giving us a solid 15.3% edge against the market when compared to his current prop line of over/under 4.5, which is good enough to mark the Under with an A- grade in our system.

Despite recent performances with 7 and 10 strikeouts, Ober is not a punch-out artist. He fanned only 120 batters in 146 and 1/3 innings last season.

Today, he will face Tampa Bay, which has the best contact lineup in the majors right now, with a mere 18.2 strikeout percentage while also posting a 103 wRC+ rating.

Ober only had seven Ks combined in his first three outings this season and was under this line in all three of them.

Let's fade him today against a tough Rays lineup.

Pick: Bailey Ober Under 4.5 Strikeouts (-154 or Better)



Tigers vs Reds Over/Under Projection

Detroit Tigers Logo
Saturday, April 25
7:15 PM ET
FOX
Cincinnati Reds Logo
Over 9.5 (+100 or Better)
FanDuel Logo

By PRO Projections

Our own Sean Zerillo projects a solid edge on the total for this matchup

While the consensus line sits at 9.5, Zerillo projects around 10.24 runs for this game, representing a nice 6.2% edge against the market, making the over the best choice with a B+ grade on our system.

Also, the number of bets and percentage of money show increasing support for this pick heading into this afternoon's first pitch.

As a reminder, you can see all of Zerillo's MLB game projections with an Action PRO Subscription. Find his projected lines every day on the PRO Projections tab.

Pick: Over 9.5 (+100 or Better)



Cubs vs Dodgers Best Bet

Chicago Cubs Logo
Saturday, April 25
7:15 PM ET
FOX
Los Angeles Dodgers Logo
Roki Sasaki Under 15.5 Outs (-170 or Better)
DraftKings Logo

By Kevork Mahserejian

Until Blake Snell returns, the Dodgers will continue rolling out their "prize" from last year's offseason, Roki Sasaki. On most teams, Sasaki's failures would not be tolerated in the rotation this long, but the Dodgers have the luxury of patience.

Sasaki's season thus far is a disaster. He has completed five full innings in just one game. However, he has also not pitched fewer than four innings in any start. The Dodgers are allowing him an ample opportunity to show them that he belongs in the rotation, but his clock is ticking.

Through 17 2/3 innings this season, Sasaki has a 6.11 ERA, 5,68 xERA, 5.17 xFIP, and a 5.07 SIERA. While his ERA is slightly worse than his peripheral stats, any number above 5.00 for a pitcher is horrendous.

Sasaki's walk rate ranks 10th-worst among all SP with at least 10 innings pitched, while his WHIP ranks eighth-worst. He is not a Dodgers-quality starter, nor would he start regularly on most teams (bottom-feeders like the Nationals would welcome him).

The only case for Sasaki pitching deep, beyond a lucky outing, is the Dodgers being stretched thin with starters in case he struggles. Justin Wrobleski would be the obvious "long man" if every SP were at full strength, but their utilization of a six-man rotation makes that unlikely.

Regardless, with Sasaki's stats thus far, the Chicago win blowing out, and the Cubs' offense ranking seventh in team wRC+ and fifth in walk rate against right-handed pitchers, do not expect him to pitch into the sixth inning.

This betting line is far more valuable than it appears. Multiple units are worth dropping on Sasaki's continued disappointment.

Read Mahserejian's full Cubs-Dodgers preview here:

Pick: Roki Sasaki Under 15.5 Outs (-170 or Better)



Sean Zerillo's Full Action App Card Today

Need more picks for Saturday's action on the diamond? It's always wise to see what our guy Zerillo is betting on!

If you haven't already, make sure you download the Action Network app and sign up for an Action PRO subscription:

Phone With the Action App Open
The must-have app for MLB bettors
The best MLB betting scoreboard
Free picks from proven pros
Live win probabilities for your bets

Author Profile
About the Author

Action Network is a team of seasoned sports betting experts specializing in a broad range of sports, from the NFL and NBA to less mainstream options like cricket and darts. Their staff includes well-known analysts like Sean Koerner and Stuckey, recognized for their accurate predictions and deep sports knowledge. The team is dedicated to delivering expert analysis and daily best bets, ensuring bettors are well-informed across all major sports.

This site contains commercial content. We may be compensated for the links provided on this page. The content on this page is for informational purposes only. Action Network makes no representation or warranty as to the accuracy of the information given or the outcome of any game or event.