The Minnesota Twins (49-53) and Washington Nationals (41-61) will meet in the MLB tonight. First pitch from Target Field is scheduled for 8:10 p.m. ET. The game will broadcast live on MLB Network.
Minnesota is a -145 favorite to win outright on the moneyline, while Washington is +120 to pull off the upset. The over/under is set at 8.5 total runs.
Continue below for my Nationals vs Twins predictions and MLB picks for Friday, July 25, as well as probable pitchers, betting trends, injury reports and more.
My Nationals vs Twins Prediction
- Nationals vs Twins pick: Nationals Moneyline (+120)
My Twins vs. Nationals best bet is on Washington moneyline, with the best line currently available at DraftKings. But as always, make sure to find the best odds by checking our live MLB odds page.
Nationals vs Twins Odds
| Nationals Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 -180 | 8.5 -105o / -115u | +120 |
| Twins Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 +150 | 8.5 -105o / -115u | -145 |
Nationals vs Twins Preview, Picks
In interleague matchups early in a series, road underdogs often hold unseen advantages, which appears to be the case in tonight's meeting between the Nationals and Twins.
These games introduce travel and scouting uncertainty, and early games feature lineups and matchups unfamiliar to bettors and models.
Public perception tends to lean too heavily on home-field advantage.
Interleague games introduce more unpredictability due to differences in lineup construction and unfamiliar opposing pitchers.
When combined with road underdog pricing, it creates exploitable inefficiencies in early matchups.
Nationals vs Twins Best Bet
- Nationals ML (+120)
