The Chicago White Sox (48-85) and New York Yankees (73-60) will face off in the MLB tonight. First pitch from Rate Field is scheduled for 7:40 p.m. ET. The game will broadcast live on CHSN.
New York is a -195 favorite to win outright on the moneyline, while Chicago is +162 to pull off the upset. The over/under is set at 9 total runs.
Continue below for my Yankees vs White Sox predictions and MLB picks for Thursday, August 28, as well as probable pitchers, betting trends, injury reports and more.
My Yankees vs White Sox Prediction
- Yankees vs White Sox pick: Yankees Moneyline (-195)
My White Sox vs. Yankees best bet is on New York moneyline, with the best odds currently available at BetMGM. But as always, make sure to find the best odds by checking our live MLB odds page.
Yankees vs White Sox Odds
| Yankees Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -125 | 9 -105 / -115 | -195 |
| White Sox Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +105 | 9 -105 / -115 | +162 |
Yankees vs White Sox Preview, Picks
This system isolates profitable late-season road favorites playing in high-humidity environments, which is the case for the Yankees in tonight's matchup against the White Sox.
By targeting teams with strong underlying performance (Pythagorean Win % 55–69%) and favorable odds, playoff-contending teams are often undervalued against weaker opponents late in the season (Game 121–159).
High humidity (70–100%) can increase offensive output, especially favoring superior teams with more depth.
Road favorites tend to be mispriced due to travel fatigue bias despite actual team quality and momentum.
This strategy exploits undervaluation in humid environments where sharp teams can "hammer" through fatigue and softer opponents.
Yankees vs White Sox Best Bet
- Yankees ML (-195)
Yankees vs White Sox Betting Trends
