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Yankees vs Twins Prediction, Pick, MLB Odds for Tuesday, September 15

Yankees vs Twins Prediction, Pick, MLB Odds for Tuesday, September 15 article feature image
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Denis Poroy-Imagn Images. Pictured: Yankees SP Max Fried

The Minnesota Twins host the New York Yankees on September 15, 2026. First pitch from Target Field is scheduled for 7:40 p.m. ET. The game will be broadcast on YES.

The Yankees are favored by -176 on the moneyline and by -1.5 on the run line. The Twins are +148 on the moneyline and +1.5 on the run line. The total is set at 7.5 runs.

Find our MLB picks and Yankees vs Twins prediction below, as well as probable pitchers, weather report, and more.


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Yankees vs Twins Prediction

  • Yankees vs Twins Pick: Max Fried Under 4.5 Strikeouts (+116)

Our Yankees vs Twins best bet is on Max Fried to record four or fewer strikeouts in this game. Make sure to find the best odds by checking our live MLB odds page, and download the Action Network app for more picks and analysis.


Yankees vs Twins Odds

Yankees Logo
Tuesday, Sep 15
7:40 p.m. ET
YES
Twins Logo
Yankees Odds
SpreadTotalMoneyline
-1.5
-104
7.5
-128o / 104u
-176
Twins Odds
SpreadTotalMoneyline
+1.5
-115
7.5
-128o / 104u
+148
Odds via FanDuel. Get up-to-the-minute MLB odds here.
FanDuel Logo
  • Yankees vs Twins moneyline: Yankees -176, Twins +148
  • Yankees vs Twins over/under: 7.5 (-128o / +104u)
  • Yankees vs Twins spread: Yankees -1.5 (-104), Twins +1.5 (-115)

Yankees vs Twins Probable Pitchers

Max Fried (LHP, NYY)StatBailey Ober (RHP, MIN)
4-4W-L7-5
3.0fWAR (FanGraphs)1.3
2.73 / 2.57ERA / xERA4.28 / 4.56
2.73 / 3.58FIP / xFIP4.57 / 4.86
16.5K-BB%10.2
47.6GB%35.0
.251BABIP.265
106Stuff+91
101Location+94

Yankees vs Twins MLB Betting Preview

Action PRO projects Yankees starter Max Fried for 4.23 strikeouts tonight against the Twins, giving us a solid 12.1% edge when compared to his current prop line of over/under 4.5, which is good enough to mark the under with a B grade in our system.

Fried will face a Minnesota lineup that has the 7th-lowest strikeout percentage in MLB at 21.1%.

Plus, the lefty has completed six frames just once in his past nine starts, and didn't even finish the fourth inning in four of them.


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Yankees vs Twins Pick, Betting Analysis

Fried has gone under this line in three of his last five games, with just four Ks in those three outings.

At plus money, let's fade him tonight against a contact-driven lineup in Minnesota.

Pick: Max Fried Under 4.5 Strikeouts (+116, FanDuel)


Yankees vs Twins Weather


Get the latest coverage on MLB Weather.


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