The Milwaukee Brewers host the Baltimore Orioles on May 20, 2025. First pitch from American Family Field is scheduled for 7:40 p.m. EDT; the game will be broadcast on MASN2.
Find my MLB betting preview and Orioles vs Brewers prediction below, as well as probable pitchers, betting trends, injury reports, and more.
My Orioles vs Brewers Prediction
- Orioles vs Brewers picks: Orioles Moneyline +110
My Orioles vs Brewers best bet is the Orioles moneyline. Make sure to find the best odds by checking our live MLB odds page.
Orioles vs Brewers Odds
| Orioles Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
+1.5 +154 | 8.5 -118o / -102u | +114 |
| Brewers Odds | ||
|---|---|---|
| Spread | Total | Moneyline |
-1.5 -185 | 8.5 -118o / -102u | -134 |
Orioles vs Brewers Projected Starting Pitchers
| Keegan Akin (BAL) | Stat | Logan Henderson (MIL) |
|---|---|---|
| 0-0 | W-L | 2-0 |
| 0.0 | fWAR (FanGraphs) | 0.3 |
| 3.27/3.79 | ERA /xERA | 2.45/2.84 |
| 4.19/4.26 | FIP / xFIP | 3.10/2.31 |
| 1.23 | WHIP | 0.82 |
| 15.2 | K-BB% | 35 |
| 31.6 | GB% | 27.3 |
| 102 | Stuff+ | 93 |
| 100 | Location+ | 108 |
Bet Labs' Orioles vs Brewers Preview
In the early games of interleague series, road underdogs can offer hidden value. These matchups come with added layers of uncertainty — travel logistics, limited scouting, and unfamiliar opponents — all of which can disrupt standard projections.
Bettors often overvalue home-field advantage, especially in interleague play, where teams face unfamiliar lineups and pitching styles. The difference in lineup structure adds further unpredictability. When these variables align with underdog pricing, they can reveal profitable opportunities that the market hasn't fully accounted for.
Orioles vs Brewers Prediction, Betting Analysis
Pick: Orioles Moneyline
Moneyline
We're backing the Orioles moneyline tonight.
Run Line (Spread)
The Orioles' moneyline offers better value tonight than the run line.
Over/Under
I'm passing on the Orioles vs. Brewers total tonight.
