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Rangers vs Guardians Prediction, Pick, Odds for Friday, September 26

Rangers vs Guardians Prediction, Pick, Odds for Friday, September 26 article feature image
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Jerome Miron-Imagn Images. Pictured: Jack Leiter

The Cleveland Guardians host the Texas Rangers on September 26, 2025. First pitch from Progressive Field is scheduled for 7:10 p.m. EDT; the game will be broadcast on MLB Network.

Find my MLB betting preview and Rangers vs Guardians prediction below, as well as probable pitchers, betting trends, injury reports and more.

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My Rangers vs Guardians Prediction

  • Rangers vs Guardians picks: Under 7.5

My Rangers vs Guardians best bet is on the under. Make sure to find the best odds by checking our live MLB odds page.


Rangers vs Guardians Odds

Rangers Logo
September 26, 2025
7:10 p.m. EDT
MLB Network
Guardians Logo
Rangers Odds
SpreadTotalMoneyline
+1.5
+134
7.5
-101o / -119u
+132
Guardians Odds
SpreadTotalMoneyline
-1.5
-169
7.5
-101o / -119u
-157
Odds via bet365. Get up-to-the-minute MLB odds here.
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Rangers vs Guardians Projected Starting Pitchers

RHP Jack Leiter (TEX)StatRHP Slade Cecconi (CLE)
9-10W-L7-6
2.0fWAR (FanGraphs)0.7
3.92 / 4.64ERA /xERA4.15 / 5.25
4.23 / 4.64FIP / xFIP4.62 / 4.07
1.31WHIP1.18
11.6%K-BB%14.2%
38.0%GB%41.3%
107Stuff+93
91Location+104

Rangers vs Guardians Prediction, Pick

BetLabs has zeroed in on the evening games, especially the Rangers vs. Guardians. Recent home team scoring league-wide has run slightly hot, and subtle environmental signals align with lower-scoring outcomes.

The market hitting the over its below 50%, suggesting minimal public pressure on inflated totals.

The Guardians have hit the over in just 20 to 67 of its last 5 games, and their previous outing against Detroit went for six runs.

Meanwhile, the wind direction—whether blowing in, across the field, or neutral—paired with moderate temperatures between 26 and 74, introduces natural resistance to run scoring.

Cleveland is competitively priced on the moneyline and has a wide win rate window, providing no clear power imbalance that might inflate totals.

When layered together, these filters isolate a soft edge in a game environment where bettors overlook the under due to recency bias and lack of extreme public conviction.

MLB Icon
Evan Abrams / Bet Labs – Night time Unders with Wind and Recency Bias
the home team's 5 Game over percentage is between 20% and 67%
the home team's previous game OU margin is between -9 and -1.5
the wind direction is To Left or In or Right To Left or Left to Right or To Right or From Right or From Left or Left To Right or None
the temperature is between 26 and 74 degrees
the home team's game number is between 2 and 160
the home team's win percentage is between 35% and 100%
the home money is between -240 and 135
the over/under % is between 2% and 50%
the game started between 19:00 and 23:59 ET
betting on the Under
$26,830
WON
1502-1148-143
RECORD
57%
WIN%

Pick: Under 7.5


Moneyline

No play here.


Run Line (Spread)

Pass on the spread.


Over/Under

The weather seems to significantly affect the total here, so we're going with the under.


Rangers vs Guardians Betting Trends



Rangers vs Guardians Weather


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